注意缺陷多动障碍患儿的功能损害特点研究

张小林, 章依文, 吴虹, 马骏, 姜艳蕊, 喻珺纯, 沈植旻

中国儿童保健杂志 ›› 2019, Vol. 27 ›› Issue (10) : 1054-1058.

PDF(614 KB)
PDF(614 KB)
中国儿童保健杂志 ›› 2019, Vol. 27 ›› Issue (10) : 1054-1058. DOI: 10.11852/zgetbjzz2019-0274
科研论著

注意缺陷多动障碍患儿的功能损害特点研究

  • 张小林1,2, 章依文1,2, 吴虹1,2, 马骏1,2, 姜艳蕊1,2, 喻珺纯1, 沈植旻1
作者信息 +

Research on the functional impairment in children with attention deficit hyperactivity disorder

  • ZHANG Xiao-lin1,2, ZHANG Yi-wen1,2, WU Hong1,2, MA Jun1,2, JIANG Yan-rui1,2, YU Jun-chun1, SHEN Zhi-min1
Author information +
文章历史 +

摘要

目的 评估注意缺陷多动障碍(ADHD)患儿的功能状态,研究不同性别、年龄段、智力水平ADHD患儿的功能损害差异。方法 2018年3月-2019年1月期间,收集疑似ADHD儿童1 718名,父母填写Weiss功能缺陷评定量表,同时专业医师按照DSM-5诊断标准对儿童进行诊断。符合诊断标准者纳入ADHD组,不满足诊断标准者纳入非ADHD组。结果 ADHD组1 011例,非ADHD组707例。在家庭、学习/学校、生活技能、自我观念、社会活动、冒险活动等维度及功能总分的功能损害方面,ADHD组均明显高于非ADHD组,两组差异均有统计学意义(Z=12.484、-15.629、-12.917、-9.435、-8.145、-11.026、-17.328,P<0.001)。在ADHD组中,男童在社会活动、冒险活动维度及总分的功能损害明显高于女童(Z=-3.322、-3.086、-2.350,P<0.05);年龄在9岁及以上组患儿在家庭、学习/学校、生活技能、自我观念、社会活动等维度及总分的功能损害,均明显高于低龄儿童(9岁以下)组(H=10.226、16.725、13.466、42.177、6.523、22.548,P<0.05);智力在中等至中下水平范围的两组(85~99,70~84)和智力低下组(<70)比智力在中等至中上水平范围的两组(100~114,115~129)在学习/学校维度有更严重的功能损害(H=54.528,P<0.05)。结论 ADHD儿童存在明显的功能缺陷,不同性别、年龄、智商水平的ADHD患儿的功能损害有不同的特点。

Abstract

Objective To assess the function in children with attention deficit hyperactivity disorder(ADHD),and to study functional impairment of ADHD children with different genders,ages,and intelligence quotient(IQ). Methods A total of 1 718 children with clinically suspected ADHD were investigated and interviewed from March 2018 to January 2019.Weiss Functional Impairment Rating Scale-Parent Report(WFIRS-P) was used to evaluate functioning of all children.ADHD group was diagnosed according to DSM-5 criteria for ADHD and children who did not meet the diagnostic criteria were assigned to non-ADHD group. Results Finally 1 011 children were in ADHD group,and 707 in non-ADHD group.ADHD children had significantly higher functional impairment than non-ADHD group in 6 dimensions,including family,school and learning,life skills,self-concept,social activities,risky activities and total score(Z=12.484,-15.629,-12.917,-9.435,-8.145,-11.026,-17.328,P<0.001).In ADHD group,boys had much severer deficits than girls in 2 dimensions of functioning such as social activities and risky activities and total score(Z=-3.322,-3.086,-2.350,P<0.05).Functional impairment of children over 9 years old were severer than children under 9 years old in family,school and learning,life skills,self-concept,social activities domains and total score(H=10.226,16.725,13.466,42.177,6.523,22.548,P<0.05).Three intelligent groups with IQ 85-99,70-84 and <70 had severer functional impairment in school and learning than other two groups with IQ 100-114 and 115-129(H=54.528,P<0.05). Conclusion ADHD children have significant functional impairment,and ADHD children with different gender,age and IQ levels show different patterns of functional impairments.

关键词

注意缺陷多动障碍 / 功能损害 / 智商 / 神经障碍性疾病

Key words

attention-deficit/hyperactivity disorder / functional / impairment / intelligence quotient / neurological disorders

引用本文

导出引用
张小林, 章依文, 吴虹, 马骏, 姜艳蕊, 喻珺纯, 沈植旻. 注意缺陷多动障碍患儿的功能损害特点研究[J]. 中国儿童保健杂志. 2019, 27(10): 1054-1058 https://doi.org/10.11852/zgetbjzz2019-0274
ZHANG Xiao-lin, ZHANG Yi-wen, WU Hong, MA Jun, JIANG Yan-rui, YU Jun-chun, SHEN Zhi-min. Research on the functional impairment in children with attention deficit hyperactivity disorder[J]. Chinese Journal of Child Health Care. 2019, 27(10): 1054-1058 https://doi.org/10.11852/zgetbjzz2019-0274
中图分类号: R749.93   

参考文献

[1] Thomas R,Sanders S,Doust J,et al.Prevalence of attention-deficit/hyperactivity disorder:a systematic review and meta-analysis[J] .Pediatrics,2015,135(4):e994-1001.
[2] Wang T,Liu K,Li Z,et al.Prevalence of attention deficit/hyperactivity disorder among children and adolescents in China:a systematic review and meta-analysis[J] .BMC Psychiatry,2017,17(1):32.
[3] American Psychiatric Association.DSM-5 Task Force.Diagnostic and statistical manual of mental disorders:DSM-5[M] .5th ed.Washington DC:American Psychiatric Association,2013.
[4] Thapar A,Cooper M.Attention deficit hyperactivity disorder[J] .Lancet,2016,387(10024):1240-1250.
[5] Thompson T,Lloyd A,Joseph A,et al.The Weiss functional Impairment Rating Scale-Parent Form for assessing ADHD:evaluating diagnostic accuracy and determining optimal thresholds using ROC analysis[J] .Qual Life Res,2017,26(7):1879-1885.
[6] 金瑜.韦克斯勒儿童智力量表(WISC-R)在上海市区的修订[J] .学校卫生,1986,8(3):1-8.
[7] 钱英,杜巧新,曲姗,等.Weiss功能缺陷量表父母版的信效度[J] .中国心理卫生杂志,2011,25(10):767-771.
[8] Kofler MJ,Sarver DE,Spiegel JA,et al.Heterogeneity in AD H D:neurocognitive predictors of peer,family,and academic functioning[J] .Child Neuropsychol,2017,23(6):733-759.
[9] Gardner DM,Gerdes AC.A review of peer relationships and friendships in youth with ADHD[J] .J Atten Disord,2015,19(10):844-855.
[10] Becker KD,Chorpita BF,Daleiden EL.Improvement in symptoms versus functioning:how do our best treatments measure up?[J] .Adm Policy Ment Health,2011,38(6):440-858.
[11] Sasser T,Schoenfelder EN,Stein MA.Targeting functional impairments in the treatment of children and adolescents with ADHD[J] .CNS Drugs,2017,31(2):97-107.
[12] Tarakcioglu MC,Gokler ME,Kadak MT,et al.Is it possible to determine the level of functional impairment that distinguishes the patients with ADHD from those without ADHD?[J] .Qual Life Res,2019,28(4):1097-1103.
[13] 顾静雯,闻萍,刘明霞,等.注意缺陷多动障碍患儿社会功能损害的情况[J] .中华实用儿科临床杂志,2015,30(8):633-634.
[14] 赵钱雷,金晶晶,李思思,等.温州市注意缺陷多动障碍患儿社会功能现况调查[J] .医学与社会,2014,27(7):76-78.
[15] Weiss MD,McBride NM,Craig S,et al.Conceptual review of measuring functional impairment:findings from the Weiss Functional Impairment Rating Scale[J] .Evid Based Ment Health,2018,21(4):155-164.
[16] Mitchison GM,Njardvik U.Prevalence and gender dfferences of ODD,anxiety,and depression in a sample of children with ADHD[J] .J Atten Disord,2015.doi:10.1177 /1087054715608442.
[17] Skogli EW,Teicher MH,Andersen PN,et al.ADHD in girls and boys--gender differences in co-existing symptoms and executive function measures[J] .BMC Psychiatry,2013,13:298.
[18] Kemper AR,Maslow GR,Hill S,et al.Attention deficit hyperactivity disorder:diagnosis and treatment in children and Aadolescents[J/OL].Rockville(MD),2018.https://www.ncbi.nlm.nih.gov/pubmed/2955 8081.
[19] 范琼丽.儿童注意缺陷多动障碍的临床检出率及其共患病研究[D] .重庆:重庆医科大学,2017.
[20] 任姣姣,岳婕,张锦妮,等.正常智商水平注意缺陷多动障碍儿童的智力结构分析[J] .中国妇幼保健,2018,33(20):4642-4645.
[21] Frazier TW,Demaree HA,Youngstrom EA.Meta-analysis of intellectual and neuropsychological test performance in attention-deficit/hyperactivity disorder[J] .Neuropsychology,2004,18(3):543-555.
[22] 孙金磊,杜亚松,江文庆,等.185例注意缺陷多动障碍患儿韦氏智力测试第Ⅳ版测量结果分析[J] .中国儿童保健杂志,2017,25(12):1192-1195.
[23] Thaler NS,Bello DT,Etcoff LM.WISC-Ⅳ profiles are associated with differences in symptomatology and outcome in children with ADHD[J] .J Atten Disord,2013,17(4):291-301.
[24] Roy A,Hechtman L,Arnold LE,et al.Childhood predictors of adult functional outcomes in the multimodal treatment study of attention-deficit/hyperactivity disorder(MTA)[J] .J Am Acad Child Adolesc Psychiatry,2017,56(8):687-695.
[25] Fried R,Chan J,Feinberg L,et al.Clinical correlates of working memory deficits in youth with and without ADHD:a controlled study[J] .J Clin Exp Neuropsychol,2016,38(5):487-496.

PDF(614 KB)

Accesses

Citation

Detail

段落导航
相关文章

/