目的 调查镇江市区4~10岁儿童性早熟发育现状及其诱发引起性早熟的相关风险因素,为防治儿童性早熟发育提供科学理论依据。方法 2016年3月-2017年3月对镇江市区9个街道共3 442名4~10岁儿童进行问卷调查和体格检查。确诊性早熟发育儿童42例,其中女童35例,男童7例,检出率为1.22%,女童性早熟检出率是男童的5倍,且检出率随着年龄增长而提高;肥胖和超重儿童性早熟检出率高于正常体重组;常服用保健滋补品、儿童饮料和人工饲养水产及动物肉类的儿童性早熟检出率明显高于对照组,且差异具有统计学意义(P< 0.05)。结论 性早熟发育的检出率较高,与日常饮食习惯及体重变化等存在一定的相关性,应当引起重视,并采取相关措施进行儿童性早熟发育的预防保健。

Objective To investigate the status of precocious puberty and risk factors for sexual precocity in children aged 4~10 years in Zhenjiang. Methods A total of 3 442 children aged 4~10 years in 9 streets in Zhenjiang were investigated by questionnaire and physical examination from March 2016 to March 2017. Results Totally 42 children were diagnosed with sexual precocious puberty,including 35 cases of girls,boys in 7 cases,and the detection rate was 1.22%.The prevalence of precocious puberty in girls was 5 times higher than that of boys,and the detection rate increased with age. The incidence of precocious puberty was higher in obese and overweight children than that in normal weight group. Children taking health supplement,drinks and artificial tonic aquatic animal breeding and meat had higher prevalence of precious puberty than the control group,and the difference was statistically significant (P<0.05). Conclusions The precocious development in children is prevalent,and is correlated with the daily diet and weight change. People′s attention and the relevant measures should be taken for the prevention and health care of precocious puberty in children.