目的 观察高频结合低频重复经颅磁刺激(HF-rTMS和LF-rTMS)对痉挛型偏瘫脑瘫患儿运动功能的影响。方法 将30例痉挛型偏瘫脑瘫患儿采用随机数字表法分为对照组和观察组,两组患儿均接受常规康复训练和受损伤半球的HF-rTMS,在此基础上对照组于未受损半球接受伪刺激,观察组接受LF-rTMS。试验前后使用粗大运动功能测试(GMFM-88)和精细运动能力测试量表(FMFM)进行评估。结果 治疗8周后,两组患儿GMFM-88评分和FMFM评分均较治疗前有改善,差异具有统计学意义(P<0.05),且观察组患儿的改善效果优于对照组,差异具有统计学意义(P<0.05)。结论 在常规康复治疗的基础上结合双侧rTMS(BL-rTMS)模式比结合单侧刺激模式更能改善痉挛型偏瘫脑瘫患儿的上肢运动功能和粗大运动功能。
Abstract
Objective To observe the effect of high-frequency combined with low-frequency repetitive transcranial magnetic stimulation (HF-rTMS and LF-rTMS) on the motor function of children with spastic cerebral palsy. Methods A total of 30 patients with spastic hemiplegic cerebral palsy were divided into two groups using a random number table method. Both groups received routine rehabilitation training and HF-rTMS on the affected hemisphere. In addition, the control group received pseudo-stimulation on the unaffected hemisphere and the observation group received LF-rTMS. Gross Motor Function Measure(GMFM)-88 and fine motor function measure (FMFM) were used to evaluate motor function before and after the session. Results Scores of GMFM-88 and FMFM in two groups were higher after the intervention with significant difference(P<0.05), especially in the observation group. Conclusion Conventional rehabilitation therapy combined with bilateral rTMS model can better improve the upper limb motor function and gross motor function of children with spastic hemiplegia cerebral palsy than the unilateral stimulation model.
关键词
重复经颅磁刺激 /
痉挛型偏瘫脑瘫 /
精细运动 /
粗大运动
Key words
repetitive transcranial magnetic stimulation /
spastic hemiplegic cerebral palsy /
fine motor /
gross motor
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