目的 分析临床痊愈的Tourette综合征(TS)患儿的主观生活质量,为TS患儿的远期干预提供依据。方法 TS组患儿129例,对照组儿童129例,所有被试者完成一般情况调查表、少儿主观生活质量问卷(ISLQ),TS组在初诊和临床痊愈时评估主观生活质量。采用χ2检验、t检验等方法,应用SPSS 20.0完成数据统计分析。结果 1)两组儿童在性别、出生体重、家庭类型、出生后4个月内的喂养情况等方面,差异有统计学意义(P<0.05);两组在年龄、家庭收入、父/母亲的文化水平以及儿童胎次等方面,差异无统计学意义(P>0.05)。2)TS组患儿主观生活质量的总得分低于健康对照组(168.08±21.28 vs 155.67±20.51),差异有统计学意义(P<0.05)。3)与临床痊愈前比较,TS组患儿临床痊愈时主观生活质量总分、家庭生活、学校生活、认知成分方面有改善,差异有统计学意义(P<0.05)。4)与对照组相比,临床痊愈的TS组患儿主观生活质量各因子得分仍不理想,差异有统计学意义(P<0.05)。结论 TS患儿临床痊愈时的主观生活质量有所改善,但与健康儿童相比,其主观生活质量仍欠佳;需继续给予规范治疗和足够的重视,不断改善其主观生活质量。
Abstract
Objective To study the subjective quality of life in clinically cured children with Tourette syndrome (TS),and to provide evidence for the long-term intervention of TS. Methods TS group including 129 cases and control group including 129 children completed a general survey and Inventory of Subjective Life Quality (ISLQ),and the case group must finish another ISLQ after cured.Chi square test and T test were used to analyze the data by SPSS 20.0 statistical software. Results 1)Children of the two groups had significant differences on gender,birth weight,family type,feeding status of 4 months after born (P<0.05);The two groups did not have significant differences on age,family income,the father/mother's education level and children's parity (Pˇ0.05).2)The total score of the subjective quality of life in TS group were lower than that in control group (168.08±21.28 vs 155.67±20.51),and the difference was statistically significant (P<0.05).3)After the clinical rehabilitation,the total subjective quality of life,family life,school life and cognitive components were improved in the TS group with significant difference (P<0.05).4)Compared with control group,all aspects of subjective quality of life in clinically cured TS group were still lower,the difference was statistically significant (P<0.05). Conclusions The subjective quality of life in children with TS has improved,but the subjective quality of life in TS patients is still poor after cured compared with normal children.Therefore,consolidation therapy and more attention should be given for the cured TS children in order to improve subjective quality of life
关键词
抽动秽语综合征 /
主观生活质量 /
儿童
Key words
Tourette syndrome /
subjective quality of life /
children
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基金
国家自然科学基金面上项目(81371499)
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