肥胖和哮喘为全球范围内的两个重要儿科疾病,随着我国经济的发展,这两个疾病在近些年发病率呈现了爆发式增长。在临床经验的基础上,通过对相关文献的回顾,证实了肥胖相关性哮喘这一表型的存在。其特点是难以控制,症状较重,对吸入糖皮质激素不敏感,发作频繁,生活质量低于其他表型。当前大多数研究只强调了对于哮喘的治疗,而忽略了肥胖对其的影响。针对肥胖相关性哮喘患儿来说,除了哮喘的治疗,也同时应该减轻体重,以改善肥胖对于疾病产生的影响。本综述的目的是探讨儿童肥胖相关性哮喘可行的治疗策略,以便更好地治疗。
Abstract
Obesity and asthma are two important pediatric diseases all over the world. With the development of economy,the incidence of these two diseases has increased dramatically in recent years. Based on the clinical experience,the phenotype of obesity related asthma is confirmed by reviewing the relevant study. The characteristics of obesity related asthma are difficult to control,severe symptoms,insensitive to inhaled glucocorticoid,frequent attacks,lower quality of life than other phenotypes. Most current studies focus on the treatment of asthma,ignoring the effects of obesity. In addition to asthma treatment,children with obesity related asthma should also lose weight to alleviate the impact of obesity on asthma. This review is aimed to explore feasible treatment strategies for obesity-associated asthma in children.
关键词
肥胖 /
哮喘 /
体重指数 /
减重治疗
Key words
obesity /
asthma /
body mass indes /
weight loss treatment
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