目的 研究重症肺炎住院患儿营养风险,探讨其与临床结局相关性,为临床营养治疗提供科学依据。方法 采用儿童营养风险及发育不良筛查工具对236例于2016年9月-2018年2月在枣强县人民医院儿科住院的1~14岁重症肺炎患儿进行营养风险筛查,根据筛查评分分为低营养风险组、中度营养风险组和高度营养风险组。空腹抽血检测总蛋白、白蛋白、前白蛋白和血红蛋白水平,同时记录机械通气时间、感染并发症、住院时间、住院总费用和营养支持应用情况等资料进行分析。结果 低营养风险患儿有28.4%(67/236),中度营养风险的有48.7%(115/236),重度营养风险的有22.9%(54/236)。1~2岁组和3~5岁组高度营养风险发生率明显高于其他两个年龄组(P<0.05);6~10岁组中度营养风险发生率明显高于其他三个年龄组(P<0.05);11~14岁组低营养风险发生率明显高于其他三个年龄组(P<0.05)。有14.0% 接受全肠外营养支持,25.5%接受肠外结合肠内营养支持,24.5%接受全肠内营养支持,36.0%没有给予任何营养支持。高度营养风险组患儿总蛋白、白蛋白、前白蛋白和血红蛋白均低于低营养风险组和中度营养风险组。高度营养风险组感染性并发症、住院时间以及住院总费用均明显高于中、低度营养风险组(P<0.05)。结论 重症肺炎患儿营养风险和临床结局密切相关,在临床上应引起重视尽快给予合理营养干预。
Abstract
Objective To explore the nutritional risk of hospitalized children with severe pneumonia and its correlation with clinical outcome,so as to provide scientific basis for clinical nutritional treatment. Methods Totally 236 children with severe pneumonia aged 1 to 14 years in Pediatrics Department of People′s Hospital in Zaoqiang County were screened for nutritional risk using the child nutrition risk and dysplasia screening tool.Total protein,albumin,prealbumin and hemoglobin levels were tested by fasting blood sampling,and data such as mechanical ventilation time,infection complications,hospitalization time,total hospitalization cost and application of nutritional support were recorded for analysis. Results Children with low,moderate and severe nutrition risk accounted for 28.4%(67/236),48.7%(115/236) and 22.9%(54/236),respectively.The rate of severe nutrition risk in children aged 1 to 2 years and 3 to 5 years was obviously higher than the other two age groups(P<0.05).Also,the low nutrition risk in children 11 to 14 year-old children was significantly higher than that in the other three age groups(P<0.05).Moreover,14.0% received total parenteral nutrition support,25.5% had parenteral combined with enteral nutrition support,24.5% underwent total enteral nutrition support,and 36.0% were not given any nutritional support.The levels of total protein,albumin,prealbumin and hemoglobin in high nutrition risk group were lower than those in low nutrition risk group and moderate nutrition risk group.Likewise,high nutrition risk group had higher incidence of infectious complications,more days of hospitalization and higher hospital expenses than moderate or low nutrition risk group(P<0.05). Conclusion The nutrition risk is closely related to clinical outcome of children with severe pneumonia,so it is supposed to give rational nutrition intervention to the high-risk children.
关键词
营养风险 /
重症肺炎 /
临床结局 /
儿童
Key words
nutritional risk /
severe pneumonia /
clinical outcome /
children
{{custom_sec.title}}
{{custom_sec.title}}
{{custom_sec.content}}
参考文献
[1] 张建华,李艳华.儿童重症肺炎临床特征和诊断治疗[J].中华临床医师杂志:电子版,2013,7(13):5715-5718.
[2] Joosten KF,Zwart H,Hop WC,et al.National malnutritionscreening days in hospitalised children in the Netherlands[J].Arch Dis Child,2010,95(2):141-145.
[3] Penagini F,Dilillo D,Borsani B,et al.Nutrition in pediatricinflammatory bowel disease:from etiology to treatment.Asystematic review[J].Nutrients,2016,8(6):334-339.
[4] 林立,李昌崇.“儿童社区获得性肺炎管理指南(2013修订)”解读[J].中华妇幼临床医学杂志:电子版,2014,10(6):728-732.
[5] Hulst JM,Zwart H,Hop WC et al.Dutch nationalsurvey to test the STRONG kids nutritional risk screening tool inhospitalized children[J].Clin Nutr,2010,29(1):106-111.
[6] 陈想英.421例儿科住院患者入院时营养状况评价[J].湖北科技学院学报:医学版,2016,30(3):249-251.
[7] Xiong L,Su Z,Liu Y,et al.Effect of family socioeconomic status on the prognosis of complex congenital heart disease in children:an observational cohort study from China [8] 卢艳萍.住院患儿入院时的营养状况调查[D].福州:福建医科大学,2017.
[9] 彭璐婷,李荣,赵卫华,等.706例外科住院患儿营养风险评估及其临床意义[J].中国当代儿科杂志,2013,15(10):880-885.
[10] 盛金叶,茅晓蒙,陆丽娜,等.住院儿童应用改良儿科营养不良风险评估工具的临床评价[J].中国实用儿科杂志,2018,33(4):281-285.
[11] Chisti MJ,Salam MA,Bardhan PK,et al.Treatment failureand mortality amongst children with severe acute malnutritionpresenting with cough or respiratory difficulty and radiologicalpneumonia[J].PLoS One,2015,10(10):e0140327