目的 了解海南农村地中海贫血(简称“地贫”)夫妇孕育的儿童体格生长发育状况,做好地贫儿童的健康促进工作。方法 对海南农村地贫夫妇所孕育的245例儿童进行问诊及体检,将检测值与参照标准进行对照评估。结果 男童和女童的生长迟缓率、低体重率、消瘦率分别依次为6.4%、24.1%、26.2%和9.6%、29.8%、24%,两者相应指标比较差异均无统计学意义;超重共3例,无肥胖者。整体上的生长迟缓率为7.8%,低体重率为26.5%,消瘦率25.3%;携带地贫基因202例占82.4%,以中间型α-地贫组的Hb平均值最低[(87.8±8.7 )g/L],且与未携带地贫基因组的Hb平均值[(116.8±16.31)g/L]比较差异有统计学意义。结论 海南农村地贫夫妇孕育儿童的营养不良状况患病率高,其贫血与地贫基因缺失或突变严重程度密切相关。因此,有必要加强携带地贫基因的儿童健康养育的指导,以提高其健康养育水平。

Objective To analyze the physical growth situation of the children with thalassemia parents in Hainan rural area,and to promote the health development for children. Methods A total of 245 children with thalassemia parents in Hainan rural area were inquired and made physical examinations.The results evaluated on the exam were compared with the reference standards. Results The prevalence rates of growth retardation,underweight and marasmus in 245 boys and girls were 6.4% vs 24.1%,26.2% vs 9.6%,and 29.8% vs 24% respectively.There was no significant difference on these indexes between boys and girls.There were 3 cases of overweight and no obesity.The overall prevalence rates of growth retardation,underweight and marasmus were 7.8%,26.5%,and 25.3%,respectively.Totally 202(82.4%) children took thalassemia gene.The Hb average value of the medium type of α-thalassemia group was the lowest (87.8±8.7)g/L,with the significant difference of (116.8±16.31) g/L to the Hb average value for no-thalassemia group. Conclusions The prevalence of malnutrition in children with thalassemia parents in Hainan rural area is higher,which is closely related to the severity of anemia and gene deficiency or mutation.Therefore,it is necessary to strengthen the guidance for health promotion in child with thalassemia,and to improve their health growing level.