目的 探索早产儿生后半年体重增长速率的影响因素,为提高早产儿生命质量提供理论依据。方法 追踪随访安徽省妇幼保健院高危儿随访中心自2012-2014年随访的174例早产儿至生后6个月,随访周期为每月随访一次,主要监测指标为体重、身长和头围;同时,收集胎龄、出生体重、合并症、高危因素、家庭情况等基线资料。采用多元回归分析方法分析影响早产儿体重增长速率的影响因素。结果 单因素方差分析显示,喂养方式、性别、小于胎龄儿、早产分类存在组间差异,且有统计学意义(P<0.05),出生体重、分娩年龄、早产合并症、妊娠合并症不同组间并未发现差异(P>0.05)。多元回归分析表明,胎龄、小于胎龄儿、性别和喂养方式是影响早产儿体重增长速率的主要因素。结论 积极个性化的营养方案对于提高早产儿体重增长速率意义深远。

Objective To explore influencing factors of weight growth rate of preterm infants post-discharge of hospital in half a year,and to provide the theoretical basis for improving the life quaity of premature infants. Methods A total of 174 premature infants were followed up from 2012 to 2014 at the following-up center of high-risk children in our hospital,with physique development parameters monitored per month till six months after discharge from the hospital.At the mean time,base line data were collected,such as gestational age,birth weight,complications,high risk factors,family back ground,etc.Multiple regression analysis was in application of analyzing the impact factors. Results ANOVA analysis showed there was difference at feeding styles,gender,small for gestational age and preterm infant classification,and it was statically significant(P<0.05).There was no significant difference at birth weight,delivery age,infant complication and pregnancy complication respectively(P>0.05).Multiple regression analysis indicated that main influencing factors of body weight growth rate of the post-charge hospital premature infants included gestational age,small for gestational age,gender and feeding style. Conclusion Personalized nutrition formula may have a far-reaching influence on weight catch-up of preterm infants.