目的 调查本地区学龄儿童血清25-羟基维生素 D[25-(OH)D],维生素A、E水平,了解学龄儿童维生素A、D、E的营养状况,为本地区学龄儿童合理补充微量营养素和预防相关疾病的发生提供理论依据。方法 收集2015年5月-2016年4月于佳木斯大学附属第一医院、建三江人民医院、宝泉岭中心医院等10余家医院门诊及住院部接受维生素A、D、E水平检测的所有6~12岁儿童资料6 030例,分别比较不同性别、年龄段、检测季节的维生素A、D、E水平和维生素营养状况差异。结果 佳木斯地区6~12岁儿童维生素A不足检出率为55.1%,充足检出率为44.9%;维生素E不足检出率为0.67%;维生素D缺乏检出率为37.9%,不足检出率为24.2%,充足检出率为37.9%;不同性别间维生素A、D、E水平比较差异无统计学意义(P>0.05)。各年龄段维生素A、D、E水平比较差异无统计学意义(P>0.05)。季节间比较差异有统计学意义 (P<0.05) 。结论 佳木斯地区学龄期儿童维生素A、D水平较低,各季节间维生素A、D、E差异明显,应引起家长及各阶层医务工作者的高度关注。
Abstract
Objective To learn the status of serum vitamin A,D,E level and the nutrition of school-aged children,and to provide the reference for the supplement of micro-nutrients and prevention of related diseases in the age group of children. Methods Totally 6 030 children from the age of six to twelve were recruited in the outpatient and inpatient departments at the First Affiliated Hospital of Jiamusi,the People's Hospital of Jiansanjiang,Central Hospital of Baoquanling etc more than 10 hospitals from May 2015 to April 2016.Vitamin A,D,E levels were directed and the differences were compared by gender,age-group and detecting season. Results The rate of lack of vitamin A was 55.1% and the adequate was 44.9%; the deficiency rate of vitamin E was 0.67% ;the lack rate of vitamin D was 37.9%,the insufficient was 24.2% and the adequate was 37.9%; The stratified analysis showed the levels of different gender was not statistically significant (P>0.05).There was no difference in different age-groups (P>0.05).There existed significantly difference in different seasons (P<0.05). Conclusion The levels of vitamin A,D are lower in school-aged children in Jiamusi area,and the differences of vitamin A,D and E are obvious in different seasons,which should arouse the attention of parents and the medical workers of all levels.
关键词
学龄儿童 /
微量营养素 /
维生素A /
维生素D /
维生素E /
维生素缺乏
Key words
school-aged children /
micro-nutrition /
vitamin A /
vitamin D /
vitamin E /
vitamin deficiency
{{custom_sec.title}}
{{custom_sec.title}}
{{custom_sec.content}}
参考文献
[1] 舒继红.脂溶性维生素佐治儿童呼吸道感染疗效观察[J].中国社区医师,2015,15(1):42 -44.
[2] Bowman BA,Russel Rm.现代营养学[M].8版.北京:化学工业出版社,2004:195.
[3] Harvey NC,Holroyd C,Ntani G,et al.Vitamin D supplementation in pregnancy:a systematic review[J].Health technology assessment (Winchester,England),2014,18(45):1.
[4] 仰曙芬,吴光驰.维生素 D 缺乏及维生素 D 缺乏性佝偻病防治建议[J].中国儿童保健杂志,2015,23(7):39-41.
[5] 丁媛慧,孙中厚.维生素 A 缺乏与儿童感染性疾病[J].中国儿童保健杂志,2016,24(1):48-50.
[6] Wong AY,chan EW,chui CS,et al.The phenomenon of micronutrient deficiency among children in China:a systematic review of the literature[J].Public Health Nutr,2014,17(11):2605-2618.
[7] 周静,刘玉梅,冯棋琴,等.海南省琼中县中小学学生血清维生素 A 水平分析[J].中国儿童保健杂志,2015,23(4):416-418.
[8] Elisabetta B.Vitamin D:a new anti-infective agent?[J].Academy of Science,2014,1317:76-83.
[9] 蒋玉艳,唐振柱,苏冰.学龄儿童维生素 D 水平与矿物元素相关性分析[J].中国食物与营养,2014,20(2):77-80.
[10] 郭旺源,欧阳飞,张健,等.不同年龄段儿童维生素 D 水平变化及其与血红蛋白的相关性[J].国际检验医学杂志,2015,36(24):3576-3577.
[11] 周为文,李晓鹏,方志峰,等.广西618名儿童青少年维生素D水平分析[J].海南医学,2016,44(3):495-496.
[12] 林涛,陈焕辉,陈翊,等.2012 年广州地区 25295 名儿童维生素 D 营养状况分析[J].中国儿童保健杂志,2013,21(8):836-839.
[13] 曾贞,郭艳,马美美,等.佛山市南海区 5017 名儿童 25-羟基维生素 D 检测结果分析[J].中国儿童保健杂志,2015,23(10):1101-1103.
[14] Fares S,Chahed MK,Feki M,et al.Status of vitamins A and E in schoolchildren in the centre west of Tunisia:a population-based study[J].Public Health Nutrition,2011,14(2):255-260.
[15] 唐咏梅,周会,刘毅,等.儿童抗氧化维生素摄入水平与抗氧化能力关系[J].中国公共卫生,2011,27(4):412-414.
[16] Samira F.Vitamin A,E,D deficiencies in tunisian very low birth weight neonates:prevalence and risk factors[J].Pediatrics and Neonatology,2014,55:196-201.