目的 了解云南独龙族少数民族地区6~24月龄婴幼儿贫血检出率和贫血类型,录求发生贫血的原因,并为“云南省贫困地区儿童营养改善项目” 营养包的服用及制定相应的干预措施提供科学依据。方法 整群抽取本地区6~24月龄婴幼儿的静脉血EDTA-K2抗凝2 ml,通过sysmex-21N血细胞分析仪分析、铁蛋白(SF)的检测、法国sebia capillarys 2 flex piercing毛细管仪血红蛋白电泳和美国伯乐CFX96 PCR仪进行地中海贫血基因检测,对结果进行统计分析。结果 本地区本群婴幼儿贫血的检出率为54.2%(65/120),以轻中度贫血为主,细胞形态以小细胞低色素为主(占比为84.2%),血清铁蛋白(SF)缺乏率57.5%,地中海贫血检出率为0%。结论 独龙族6~24月婴幼儿贫血的检出率仍较高,且以缺铁性贫血为主,服用“云南省贫困地区儿童营养改善项目” 营养包对改善贫血有一定的帮助。
Abstract
Objective To find out the rate,type and cause of anemia of 6 to 24 months old infants from Yunnan Drung minority area,and to provide a scientific basis for nutrition package taking of "Yunnan poor areas children's nutrition improvement project" and the prevention anemia measures. Methods Using cluster samping method,the vein blood of local area 6~24 months old infants collected,and analysis was detected serum ferritin (SF) by sysmex-21N blood cell analyzer,the SEBIA capillarys 2 flex piercing hemoglobin electrophoresis analyzer was used for hemoglobin electrophoresis,the BIO-RAD CFX96 PCR was used to diagnose thalassemia gene.Finally,all data were carried on the statistical analysis. Result Local infant anemia incidence rate was 54.2% (65/120),the major anemia type was mild anemia,wich cell morphology was in cellule low pigment based (accounted for 84.2%),SF lack was 57.5%,Thalassemia was 0%. Conclusions The anemia incidence rate is more higher among 6~24 months infant of Drung minority.The major type of anemia was iron deficiency anemia,that is extraordinary important guiding for taking the nutrition package.
关键词
独龙族 /
儿童 /
贫血
Key words
Drung ethnic minority /
infant /
anemia
{{custom_sec.title}}
{{custom_sec.title}}
{{custom_sec.content}}
参考文献
[1] 中国公共卫生科学数据中心.2000 年儿童贫血率[EB /OL].http://www.phsciencedata.on/ActDream/jsp/customer/
[2] WHO,UNICEF,UNU.Iron deficiency anaemia:assessment,prevention and control,a guide for programme managers[R].Geneva,World Health Organization,2011.http://www.who.int/nutrition/publications/micronutrients/anaemia_iron_deficiency/WHO_NHD_01.3/en/index.html,consultado el 7 Junio 2011
[3] 葩丽泽·买买提,魏学燕,张格祥,等.新疆贫困地区0~6岁儿童贫血状况分析[J].现代预防医学 2014,41(8):1400-1402.
[4] 李晓智.缺铁性贫血的诊断治疗进展[J].中国医药指南, 2013,11(17):492-493.
[5] 徐湘民.地中海贫血预防控制操作指南[M].北京:人民军医出版社,2011:55-57.
[6] 张爱玲,张敬旭,王燕.中国中西部 46县 6 ~ 35月龄儿童贫血状况研究[J].中国儿童保健杂志,2009,17(3):260-264.
[7] 姚莉琴,全星,邹团标,等 云南佤、拉祜、纳西、白族儿童地中海贫血及葡萄糖-6-磷酸脱氢酶缺乏症的调查[J].广东医学, 2012,33(18):2826-2828.
[8] Chen CHM,He W,Wang YY,et al.Nutritional status of children during and post-global economic crisis in China[J].Biomed Environ Sci,2011,24(4):321-328.
[9] 蒋祥林.重庆市万州地区0~6岁儿童贫血的发病率、病因分析及防治措施[J].中国妇幼保健,2014,29(19):3046.