目的 了解乌鲁木齐市高新区儿童麻疹抗体免疫状况,为制定免疫对策提供科学依据。方法 采用整群抽样法抽取高新区6所学校3~15岁儿童共560人,采用酶联免疫法定性测定麻疹IgG抗体水平检测。结果 乌鲁木齐市高新区3~15岁儿童麻疹总体抗体阳性率92.32%,其中不同年龄组、性别、民族、现居住地、免疫史、既往麻疹患病史的抗体阳性率差异均无统计学意义(P≥0.05)。麻疹患病率为1.43%。接种1剂次及2剂次疫苗者血清抗体阳性率差异无统计学意义(P≥0.05)。本市人口的抗体阳性率高于流动人口,并且随着年龄组的增高而抗体阳性率降低,差异有统计学意义(P＜0.05)。结论 流动儿童麻疹抗体水平有待进一步提高,开展流动儿童强化免疫是消除麻疹重要措施。

Objective To investigate measles antibodies level of children in High-tech district of Urumqi and to provide the scientific basis for the development of immunization countermeasures. Methods A total of 560 students aged 3 to 15 were selected from six schools in High-tech district of Urumqi by cluster sampling.The serum IgG levels of measles antibody were detected by ELISA. Results 3~15 years old children's overall measles antibody positive rate was 92.32% in High-tech district of Urumqi.The antibody positive rates were no statistically significant different (P≥0.05) in different groups of different ages,genders,nationalities,places of residence and history of measles disease respectively.The prevalence of measles was 1.43%.The antibody positive rates of different dose were no statistically significant different (P≥0.05).The antibody positive rates of civil population was higher than that of the floating population (P<0.05).The antibody positive rates increased with the growth of age while decreased with the growth of dose vaccination (P<0.05). Conclusion Floating children measles antibody levels remains to be further improved,so the proper supplementary immunization activities (SIAs) implementation is important for elimination of measles.