孤独症与肠道菌群失衡的研究进展

傅锦坚; 张玉; 李红辉

doi:10.11852/zgetbjzz2017-25-03-12

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中国儿童保健杂志 ›› 2017, Vol. 25 ›› Issue (3) : 255-257. DOI: 10.11852/zgetbjzz2017-25-03-12

综述与讲座

孤独症与肠道菌群失衡的研究进展

傅锦坚¹,张玉²,李红辉³

作者信息 +

Important roles for the gut microbiome in autism spectrum disorder

FU Jin-jian¹,ZHANG Yu²,LI Hong-hui³

Author information +

文章历史 +

摘要

研究显示孤独症谱系障碍(ASD)患者存在明显的胃肠道症状及肠道菌群改变情况,失调的细菌极有可能是ASD疾病发生发展的潜在生物标记物。对肠道微生物的研究,尤其是共生微生物的研究将有助于了解肠道微生物与ASD疾病发生发展的关系。本文就ASD与肠道微生物的关系做一简要综述,为探讨肠道菌群作为ASD靶向治疗的潜在靶点提供理论依据。

Abstract

Studies show that most of patients with autism spectrum disorders (ASD) have significant gastrointestinal (GI) symptoms and gut microbiome disorders.These bacterias may be the potential biomarkers of ASD.Studies of microbiome in ASD suggest that changes in the gut microbiome may be associated with ASD and GI disorders in children with ASD.This article reviews the relationship between intestinal bacteria and ASD,and provide a theoretical basis by discussing gut microbiomes as a potential target for ASD therapy.

导出引用

傅锦坚,张玉,李红辉. 孤独症与肠道菌群失衡的研究进展[J]. 中国儿童保健杂志. 2017, 25(3): 255-257 https://doi.org/10.11852/zgetbjzz2017-25-03-12

FU Jin-jian,ZHANG Yu,LI Hong-hui. Important roles for the gut microbiome in autism spectrum disorder[J]. Chinese Journal of Child Health Care. 2017, 25(3): 255-257 https://doi.org/10.11852/zgetbjzz2017-25-03-12

中图分类号： R179

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