目的 通过分析末梢血钙、锌、铁、镁、铜水平与儿童反复呼吸道感染(RRTI)的相关性,进而评价各元素水平在RRTI儿童中的意义。方法 以2015年11月-2016年3月在承德市中心医院儿科门诊就诊或体检准备行末梢血元素检测的6个月~4岁儿童为研究对象,随机抽取患有RRTI儿童132例为研究组,并将同期门诊体检的健康儿童设为对照组,其中每组按年龄分三个年龄段,1岁以下、1～2岁和2岁以上。采用北京博晖BH5100S型原子吸光光谱仪测定元素水平。测定数据采用SPSS 19.0统计学软件分析。结果 1)研究组与对照组各年龄段血锌水平、1岁以下血钙水平、2岁以上血钙和血铁水平比较,差异均有统计学意义(P<0.05或<0.01);各年龄段血镁、血铜水平比较,差异均无统计学意义(P均>0.05)。2)五种元素的相关性分析,钙、锌、铁三者之间呈正相关。结论 RRTI儿童与锌元素缺乏密切相关,与钙、铁元素缺乏也存在一定的关系,三者之间在代谢过程中可能存在协同作用。

Objective To evaluate the value of the level of peripheral blood elements in children with recurrent respiratory tract infection(RRTI),and study the relationship between peripheral blood elements and RRTI in children. Methods The registered data of elements in peripheral blood examination was collected in Chengde Central Hospital pediatric clinic from November 2015 to March 2016.6 months to 4 years old children were randomly selected as the research object.132 cases of children suffering from RRTI were study group,and the healthy children of the same period were set up as the normal control group.Children in each group were divided into three age groups,under 1 year of age group,1~2 years old group and >2 years older group.In this study,Beijing Bohui BH5100S atomic absorption spectrometer were employed to determine the children's peripheral blood.Data were analyzed by SPSS 19.0 statistical software. Results 1)The levels of blood zinc had significant differences (P<0.01) between RRTI group and the control in children among different ages.There were also statistical significance (P<0.05) in the level of blood calcium between two groups in children under 1 year old.Moreover,there were statistical significances (P<0.05) in the levels of blood calcium and iron between two groups in children of >2 age,and the level of iron reached significant level too (P<0.01).2)According to the correlation analysis of five trace elements,the result indicated that calcium,zinc and iron were positively correlated. Conclusion The RRTI is related to the lack of zinc,and there is a certain relationship with the deficiency of calcium and iron,and there might be synergistic effects in the metabolism process among them.