目的 采用事件相关电位(ERP)对纠正胎龄1周早产儿与生后1周足月儿的认知进行比较研究,探索早产儿早期认知特征。方法 随机选择健康足月儿(1~7 d)30名、早产儿(纠正胎龄1~7 d)15名。采用听觉oddball范式,记录听觉事件相关电位(aERP),对两组进行Fz、Cz导联P2、N2波面积比较分析。结果 1)Fz导联,P2、N2波面积早产儿组均小于足月儿组,差异有统计学意义(t=2.133,P=0.039;t=2.230,P=0.031);2)Cz导联,P2、N2波面积早产儿组均小于足月儿组,差异有统计学意义(t=2.107,P=0.041;t=2.179,P=0.035)。结论 早产儿(纠正胎龄)第一周感知、识别声音等认知功能落后于同日龄足月儿。
Abstract
Objective To compare the cognitive of preterm infants (corrected gestational age) and full-term infants in first week with event related potential (ERP),and to explore the cognitive characteristics of preterm infants. Methods 30 healthy full-term infants (1~7 days) and 15 premature infants (corrected age of 1~7 days) were randomly selected.The auditory event related potential (aERP) was recorded with auditory oddball paradigm,and P2 and N2 wave area on the Fz,Cz lead of the two groups were compared. Results 1)Fz lead,there were significant differences of the P2 and N2 wave area between premature and in full-term infants (t=2.133,P=0.039;t=2.230,P=0.031);2)Cz lead,there were significant differences of the P2 and N2 wave area between premature and in full-term infants (t=2.107,P=0.041;t=2.179,P=0.035). Conclusion Cognitive functions such as voice perception and recognition of preterm infants (corrected gestational age) developed more solely than full-term infants of the same day age in the first week.
关键词
早产儿 /
足月儿 /
第一周 /
认知 /
事件相关电位
Key words
premature infants /
full-term infants /
the first week /
cognitive /
event related potential
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基金
江苏省自然科学基金-面上项目(BK20161194);常州市科技支撑计划项目(CE20135045)
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