新生儿B族溶血链球菌的耐药性及疫苗研究进展

苏锦珍,丁璐,吴本清

中国儿童保健杂志 ›› 2016, Vol. 24 ›› Issue (11) : 1174-1176.

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中国儿童保健杂志 ›› 2016, Vol. 24 ›› Issue (11) : 1174-1176. DOI: 10.11852/zgetbjzz2016-24-11-16
·综述与讲座·

新生儿B族溶血链球菌的耐药性及疫苗研究进展

  • 苏锦珍,丁璐,吴本清
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摘要

新生儿B族溶血链球菌属β溶血链球菌(GBS)。由于对有危险因素的孕妇预防使用抗生素,新生儿GBS感染的发生率有所下降,但GBS耐药率有上升趋势。GBS耐药的主要血清型为血清型Ⅲ、Ⅰa、Ⅰb、Ⅱ、Ⅴ型,目前发现的大环内酯类抗生素耐药基因有ermA、ermB、mefA/E和linB等。疫苗的研究主要建立在血清型、ST-17基因的基础上,其中血清型主要集中于Ⅲ型及Ⅴ型。

关键词

新生儿 / 无乳链球菌 / 耐药性 / 耐药基因 / 疫苗

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苏锦珍,丁璐,吴本清. 新生儿B族溶血链球菌的耐药性及疫苗研究进展[J]. 中国儿童保健杂志. 2016, 24(11): 1174-1176 https://doi.org/10.11852/zgetbjzz2016-24-11-16
中图分类号: R179   

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