目的 筛查与分析新生儿眼底疾病的发病情况。方法 回顾性分析济南市妇幼保健院2014年9月1日-2015年8月31日出生的新生儿眼底筛查情况。将新生儿按照儿科指征分为正常新生儿组、高危儿组和未成熟儿组,比较三组眼底异常情况有无差异。结果 11 553名新生儿中,3 001(25.98%)例新生儿伴有眼底异常。正常新生儿组眼底异常检出率为25.20%(2 512/9 967);高危儿组眼底异常检出率31.96%(272/851),明显高于正常新生儿组;未成熟儿组眼底异常检出率29.52%(217/735),也明显高于正常新生儿组。结论 高危儿和未成熟儿的眼底异常明显高于正常新生儿,通过新生儿眼底筛查可以早期发现,为患儿的早期治疗、挽救视力乃至生命赢得时机。
Abstract
Objective To screen and analyze the incidence of retinopathy in newborns. Methods Retinopathies in newborns born from September 1,2014 to August 31,2015 in our hospital were analyzed retrospectively.All newborns were classified into 3 groups:normal newborns,high-risk newborns,and premature newborns according to their clinical conditions.Incidence of retinopathy in normal newborns was compared with high-risk newborns and premature newborns separately. Results Overall,3 001 of 11 553 (25.98%) newborns were found to have retinopathy.The incidence of retinopathy among normal newborns was 25.20% (2 512/9 967).The incidence among high-risk newborns was 31.96%(272/851),and higher than that in normal newborns.In addition,the incidence among premature newborns(29.52%,217/735) was also higher than that in normal newborns. Conclusions The incidences of retinopathy in high-risk newborns and premature newborns are significantly higher than that in normal newborns.Early screening can contribute to early detection and intervention of retinopathy in newborns,and help saving visions and even lives.
关键词
新生儿 /
视网膜病 /
普筛 /
眼底照相
Key words
newborn /
retinopathy /
screening /
fundus imaging
{{custom_sec.title}}
{{custom_sec.title}}
{{custom_sec.content}}
参考文献
[1] Kuhrt H,Gryga M,Wolburg H,et al.Poetnatal mammalian retinal development:quantitative data and general rules[J].ProgRetin Eye Res,2012,31:605-621.
[2] 张琦,赵培泉.家族性渗出性玻璃体视网膜病变的荧光素眼底血管造影特征及其诊断价值[J].中华眼底病杂志,2011,27(3):263-266.
[3] 张琦,费萍,赵培泉.903名婴儿RetcamⅡ检查临床分析[J].上海交通大学学报,2013,33(8):1126-1129.
[4] Kashani AH,Learned D,Nudleman E,et al.High prevalence of peripheral vascular anomalies in family members of patients with familial exudative vitreoretinopathy[J].Ophthalmology,2014,121(1):262-268.
[5] 殷纳新,袁进,陈家祺,等.新生儿视网膜出血广域数字化眼底成像系统分析[J].中国时用眼科杂志,2013,31(2):191-193.
[6] 郭燕.婴幼儿4860例眼底检查结果与分析[J].国际眼科杂志,2013,13(3),607-610.
[7] Jalali S,Kesarwani S,Hussain A.Outcomes of a protocol-based management for zone 1 retinopathy of prematurity:the indian twin cities ROP screening program report number 2[J].Am J Ophthalmol,2011,151(4):719-724.
[8] Chen J,Stahl A,Hellstrom A,et al.Current update on retinopa-thy of prematurity:screening and treatment[J].Curr O pin Pediatr,2011,23(2):173-178.
[9] Hellstrom A,Smith LE,Dammann O.Retinopathy of prematurity[J].Lancet,2013,382(9902):1445-1457.
[10] Jasani B,Nanavati R,Kabra N.Mechanisms and management of retinopathy of prematurity[J].N Engl J Med,2012,367(26):2515-2526.
[11] Choi YJ,Jung MS,Kim SY.Retinal hemorrhage asso-ciated with perinatal distress in new borns[J].Korean J Ophthalmol,2011,25(5):311-316.
[12] Li LH,Li N,Z hao JY,et al.Findings of perinatal ocular examination performed on 3573 healthy full-term new -borns[J].Br J Ophthalmol,2013,97(5):588-591.
[13] 北京早产儿视网膜病变流行病学调查组.北京早产儿视网膜病变筛查和高危因素分析[J].中华眼底病杂志,2008,24:30-34.
[14] Criswick VG,Schepens CL.Familial exudative vitreoretinopathy[J].Am Ophthalmol,1969,68:578-594.
[15] Akabane N,Yamamoto S,Tsukahara I,et al.surgical outcomes in juvenile retinal detachment[J].Jpn J Ophthalmol,2001,45:409-411.
[16] Yokoyama T,Kato T,Minamoto A,et al.Characteristics and surgical outcomes of pediatric retinal detachment[J].Eye,2004,18:889-892.
[17] 罗俊,郭燕.熊师,等.婴幼儿眼底渗出样改变489例临床分析[J].医学临床研究,2014,31(7):1316-1317.