目的 分析乙肝疫苗事件对儿童疫苗接种和家长疫苗选择的影响、评估影响程度和持续时间。方法 收集2011-2014年深圳市福田区儿童常规免疫疫苗使用情况,重点对2013-2014年疫苗使用数据进行分析。结果 2014年一类疫苗用量较2013年减少8.57%,2014年1月一类疫苗、一类乙肝疫苗用量为疫苗事件后最低,较2013年同期下降43.24%、50.38%,影响较大的时间为疫苗事件后3个月。疫苗事件后二类疫苗用量稳步上升,用量较2013年上升8.64%。2014年一类疫苗替代疫苗使用比例达39.38%,较2013年上升11.57%。结论 乙肝疫苗事件后儿童一类疫苗接种受到影响,家长选择二类疫苗意愿增加,应加大一类疫苗免疫效果和安全性宣传,恢复家长接种信心。

Objective To explove the influence of Hepatitis B vaccine (HBV) event on children's immunization,assess the extent and lasting time. Method The data of vaccines use of children's routine immunization were collected from 2011 to 2014 and focused on data from 2013 to 2014. Results The usage of first type vaccines in 2014 was decreased 8.57% compared to 2013,the lowest month was January 2014,first type vaccines and free HBV vaccine felled 43.24% and 50.38% compared with the same period in 2013.After HBV vaccine event,usage of the second type vaccine was increased steadily,rose 8.64% compared with 2013.The substitute ratio of first type vaccine was 39.38% in 2014,rose 11.57% compared with 2013. Conclusion The HBV event had caused a great impact on first type vaccine immunization,the wishes of parents to choose second type vaccine increased,we should enhance propaganda on efficacy and safety of first type vaccine,restore parents' vaccination confidence.