目的 分析新生儿呼吸窘迫综合征患儿维生素A、矿物质的水平,为新生儿呼吸窘迫综合征(NRDS)的防治提供理论依据。方法 以2011年1月-2011年12月在德州市人民医院新生儿科监护室住院治疗确诊为新生儿呼吸窘迫综合征的40例患儿作为观察组,同期住院的无呼吸障碍的新生儿30例作为对照组。入院后24 h内采集空腹股静脉血2 ml化验维生素A、钙、镁、铜、铁、锌浓度。结果 NRDS组患儿血清维生素A浓度较对照组降低,差异有统计学意义(P<0.01)。NRDS组患儿血清铁、锌的浓度较对照组降低,差异有统计学意义(P<0.05)。NRDS组患儿与对照组新生儿血清钙、镁、铜的差异无统计学意义(P>0.05)。结论 维生素A、铁、锌在促进新生儿肺组织发育,提高肺表面活性物质的含量和活性,降低肺表面张力方面有一定的作用,减少了呼吸窘迫综合征的发生和严重程度。
Abstract
Objective To observe the levels about vitamin A and mineral with neonatal respiratory distress syndrome (NRDS). Methods A total of 40 neonates with NRDS were chosen as research group in the neonatal department of Dezhou People's Hospital,and 30 healthy neonates were enrolled into the study as control group.The levels of vitamin A,calcium,magnesium,copper,iron and zinc were detected from venous blood at 24 h after being admitted to hospital. Result The level of vitamin A in the research group were lower than that in the control group (P<0.01),The levels of iron and zinc in the research groups were lower than those in the control group (P<0.05),and there were no significant differences on the levels of calcium,magnesium and copper between two groups (P>0.05). Conclusions Vitamin A,iron and zinc could promote the development of the lung tissue,enhance the content and activity of the pulmonary surfactant and reduce the occurrence rate and the severity of NRDS.
关键词
新生儿呼吸窘迫综合征 /
维生素A /
矿物质
Key words
neonatal respiratory distress syndrome /
vitamin A /
mineral substance
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