目的 研究孤独谱系障碍(autism spectrum disorder,ASD)患儿的症状特点、心理问题及对父母情绪障碍的影响。方法 分别使用孤独症行为量表和长处与困难问卷对593名患儿进行行为学表现和心理评估,同时使用抑郁自评量表、焦虑自评量表评估患儿父母的情绪障碍表现。结果 在情绪及多动注意不能和困难总分方面,高年龄组的患儿表现出了更多的困难(F=4.361,P=0.013;F=16.029,P=0.000;F=9.638,P=0.013),同时在亲社会行为方面,高年龄组则表现更好(F=11.052,P=0.000);无论在焦虑或是抑郁障碍,母亲更易患情绪障碍(χ2=15.893,P=0.000;χ2=27.592,P=0.000);父母的抑郁,焦虑情绪与ASD患儿的多个行为学表现维度相关,并直接受症状严重程度的影响。结论 ASD患儿行为学表现在不同年龄段表现不同,体现在情绪、多动注意不能及亲社会行为方面;母亲往往比父亲更易患有情绪障碍,父母亲的情绪障碍受ASD患儿的多个行为表现维度影响,应引起注意。
Abstract
Objectives To investigate the symptom,behavior characteristics and parental mood disorders of the children with autism spectrum disorder (ASD). Method Totally 593 ASD children were tested by Autism Behavior Checklist (ABC) and Strengths and Difficulties Questionnaire (SDQ),and parental mood disorders were evaluated with Zung Self-Rating Depression Scale (SDS) and Zung Self-Rating Anxiety Scale (SAS). Results Compared to lower age group,the higher age group showed more difficult in mood subscale,hyperactivity subscale and total points(F=4.361,P=0.013;F=16.029,P=0.000;F=9.638,P=0.013),and the higher group presented better in prosocial behavior dimension (F=11.052,P=0.000);Compared to fathers,mothers were apt to suffer from mood disorders in both depression or anxiety disorders (χ2=15.893,P=0.000;χ2=27.592,P=0.000);Parental depression and anxiety were related with various behavior performance,and were directly affected by the severity of the symptoms of their ASD children. Conclusions Children with ASD behave different with age,reflected in mood,hyperactivity and prosocial behavior dimensions;Mothers are more easily afflicted with mood disorders than fathers,and parental emotional disorders are positive correlated with the severity of symptoms in various behavior problems,which is worthy of attention.
关键词
孤独谱系障碍 /
行为症状 /
父母 /
情绪障碍
Key words
autism spectrum disorder /
behavior symptom /
parents /
mood disorder
{{custom_sec.title}}
{{custom_sec.title}}
{{custom_sec.content}}
参考文献
[1] Jones W,Klin A.Attention to eyes is present but in decline in 2-6-month-old infants later diagnosed with autism[J].Nature,2013, 504(7480):427-431.
[2] Ozonoff S,Young GS,Belding A,et al.The broader autism phenotype in infancy:when does it emerge?[J].J Am Acad Child Adolesc Psychiatry,2014,53(4):398-407.
[3] Johnny L,Alison M.The increasing prevalence of autism spectrum disorders[J].Res Autism Spect Dis,2011,5(5):418-425.
[4] 刘靖,杨晓玲,贾美香,等.2004年北京市2~6岁儿童广泛性发育障碍的现况调查[J].中国心理卫生杂志,2007,2l(5):290-293.
[5] Hyman SL,Rodier PM,Davidson P.Pervasive developmental disorders in young children[J].JAMA,2001,285(24):3141-3142.
[6] Diagnostic and Statistical Manual of Mental Disorders,Fifth Edition(DSM V)[S].Washington DC:American Psychiatric Association,2013.
[7] Baxter AJ,Brugha TS,Erskine HE,et al.The epidemiology and global burden of autism spectrum disorders[J].Psychol Med,2014,11(8):1-13.
[8] Olsson MB,Hwang CP.Depression in mothers and fathers of children with intellectual disability[J].J Intellect Disabil Res,2001,45(Pt 6):535-543.
[9] Krug DA,Arick J,Almond P.Behavior checklist for identifying severely handicapped individuals with highlevels of autistic behavior[J].J Child Psychol Psychiatry,1980,21(3):221-229.
[10] 寇建华,杜亚松.儿童长处和困难问卷与儿童行为量表相关性研究[J].临床精神医学杂志,2009,19(5):317-319.
[11] Zung WW,Richards CB,Short MJ.Self-rating depression scale in an outpatient clinic:further validation of the SDS[J].Archives of General Psychiatry,1965,13(6):508.
[12] Zung WW.A rating instrument for anxiety disorders[J].Psychosomatics:Journal of Consultation Liaison Psychiatry,1971,12(6):371.
[13] Firth I,Dryer R.The predictors of distress in parents of children with autism spectrum disorder[J].J Intellect Dev Disabil,2013,38(2):163-171.
[14] 龚云,杜亚松,李惠琳.孤独症患儿父母压力和情绪变化及相关因素[J].中国儿童保健杂志,2012,20(4);297-301.
[15] Junior SBM,Celestino MI,Serra JP,et al.Risk and protective factors for symptoms of anxiety and depression in parents of children with autism spectrum disorder[J].Dev Neurorehabil,2014,20(1):1-8.
[16] Barnes J,Kroll L,Lee J,et al.Communication about parental illness with children who have learning disabilities and behavioural problems:Three case studies[J].Child Care Health and Development,1998,24(5):441-456.
[17] Weiss MJ.Hardiness and socied support as predictors of stress in mothers of typical children,children with authism,and children with mental retardation[J].Autism,2002,6(1):115-130.
基金
国家重点基础研究发展计划(973) (2010CB529602);上海市科委重点项目(11411952401);上海交通大学医工交叉重点项目(YG2013ZD0503)