足月小于胎龄儿早期生长追赶与胰岛素抵抗相关性研究

周彬婷; 林艳

doi:10.11852/zgetbjzz2015-23-02-02

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中国儿童保健杂志 ›› 2015, Vol. 23 ›› Issue (2) : 116-118. DOI: 10.11852/zgetbjzz2015-23-02-02

科研论著

足月小于胎龄儿早期生长追赶与胰岛素抵抗相关性研究

周彬婷¹，林艳²

作者信息 +

Study on catch-up growth correlation with insulin resistance in children with full term small for gestational age.

ZHOU Bin-ting¹,LIN Yan².

Author information +

文章历史 +

摘要

目的旨在探讨2~4岁足月小于胎龄儿出生后早期生长追赶与胰岛素抵抗的关系。方法采用1∶1配对的研究方法，分析44对足月小于胎龄(small for gestational age，SGA)儿和足月适于胎龄(appropriate for gestational age，AGA)儿的生长发育情况及稳态模型的胰岛素抵抗指数、胰岛素敏感性指数、胰岛β细胞功能指数，及生长追赶与以上指标的关系。结果 SGA儿出生时生长发育指标、0~6月龄期生长追赶指标与AGA儿差异均有统计学意义(P<0.05)。2～3岁组、3～4岁组SGA儿胰岛素抵抗指标低于AGA儿，胰岛素敏感指标高于AGA儿，差异均有统计学意义(P<0.05)。小于4岁组0~6月龄期身长Z积分增值与Homa-IAI呈正相关;大于4岁组7~12月龄期体重Z积分增值与Homa-IR呈正相关。结论 SGA儿早期存在明显的生长追赶现象，尚未出现胰岛素抵抗，胰岛素敏感、胰岛素抵抗的改变都是随着时间的推移而出现逐渐变化的过程。

关键词

足月小于胎龄儿 / 早期生长追赶 / 胰岛素抵抗

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导出引用

周彬婷，林艳. 足月小于胎龄儿早期生长追赶与胰岛素抵抗相关性研究[J]. 中国儿童保健杂志. 2015, 23(2): 116-118 https://doi.org/10.11852/zgetbjzz2015-23-02-02

ZHOU Bin-ting,LIN Yan.. Study on catch-up growth correlation with insulin resistance in children with full term small for gestational age.[J]. Chinese Journal of Child Health Care. 2015, 23(2): 116-118 https://doi.org/10.11852/zgetbjzz2015-23-02-02

中图分类号： R725.8

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