目的 分析 Tourette 综合征(Tourette syndrome,TS)儿童的主观生活质量和社会适应能力,为临床治疗提供指导依据。方法 采用儿少主观生活质量问卷(Inventory of Subjective Life Quality,ISLQ)、儿童行为量表(Children Behavior Checklist,CBCL)、儿童适应行为评定量表(Social of Adaptive Behavior,SAB),对112例 TS 儿童( ≥8岁)的主观生活质量和社会适应能力进行对照研究。结果 TS 患儿 ISLQ 中有7个维度得分明显低于对照组(P＜0.01);行为问题得分明显高于对照组(P＜0.05)。适应能力商数(adaptability quotient,ADQ)低于对照组(P＜0.05),其中认知功能、社会/自制两项与对照组差异有高度统计学意义(P＜0.001)。结论 TS 儿童的主观生活质量和社会适应能力存在诸多问题,及时进行合理干预,有助于促进 TS儿童身心康复。

Objective To analysis the subjective living-quality and the social adaptive behavior in children with Tourette syndrome (TS) and to provide guidance for clinical treatment. Methods The subjective living-quality and the social adaptive behavior of 112 TS children (≥8 years old) were measured by means of Inventory of Subjective Life Quality (ISLQ),Children Behavior Checklist (CBCL) and Social of Adaptive Behavior (SAB) scales. Results The 7 aspect scores of ISLQ (in fact,7 aspects of them) in TS children were lower than those in control group (P＜0.01).The scores of behavior problems in TS children was higher than that in control group (P＜0.05).The ADQ in TS children was lower than that in control group (P＜0.05).Particularly the cognitive function and social /self direction were lower than those in control group(P＜0.001). Conclusions There are many problems in TS children' subjective living-quality and social adaptive behavior.Appropriate intervention should be given timely to promote the psycho-behavioral rehabilitation of TS children.