doi:10.11852/zgetbjzz2016-24-02-12

Abstract

摘要： 随着新生儿重症监护病房的建立和技术发展,危重早产儿存活率明显提高,但部分存活早产儿遗留脑瘫、运动发育迟缓、视听觉损害等神经发育障碍,严重影响早产儿的生存质量。早产儿远期的不良结局与营养、严重并发症等因素有关。早产儿神经元的发育可能延续至2岁,因此,对早产儿出院后的长期密切随访、评估,对发育异常者及时积极干预等措施可改善其神经系统发育结局。

关键词: 早产儿, 神经发育, 结局, 评估, 早期干预

CLC Number:

R722

黄海燕. 早产儿神经系统发育结局的研究进展[J]. 中国儿童保健杂志, 2016, 24(2): 153-155.

[1] Mwaniki MK,Atieno M,Lawn JE,et al.Long-term neurodevelopmental outcomes after intrauterine and neonatal insults:a systematic review[J].Lancet,2012,379(9814):445-452.
[2] Stiles J,Jernigan TL.The basics of brain development[J] Neuropsychology Review.2010,20(4):327-348.
[3] Ortinau C,Neil J.The neuroanatomy of prematurity:normal brain development and the impact of preterm birth[J].Clinical Anatomy,2015,28(2):168-183.
[4] Lind A,Parkkola R,Lehtonen L,et al.Associations between regional brain volumes at term-equivalent age and development at 2 years of age in preterm children[J].Pediatric Radiology,2011,41(8):953-961.
[5] Vohr BR.Neurodevelopmental outcomes of extremely preterm infants[J].Clinics in Perinatology,2014,41(1):241-255.
[6] 刘云峰,周丛乐,郭在晨,等.早产儿脑额叶发育及其影响因素的研究[J] 临床儿科杂志,2008,26(3):173-177.
[7] Nash A,Dunn M,Asztalos E,et al.Pattern of growth of very low birth weight preterm infants,assessed using the WHO Growth Standards,is associated with neurodevelopment[J].Appl Physiol Nutr Metab,2011,36(4):562-569.
[8] Titomanlio L,Kavelaars A,Dalous J,et al.Stem cell therapy for neonatal brain injury:perspectives and challenges[J].Annals of Neurology,2011,70(5):698-712.
[9] Morse SB,Zheng H,Tang Y,et al.Early school-age outcomes of late preterm infants[J].Pediatrics,2009,123(4):e622-629.
[10] Kerstjens JM,de Winter AF,Bocca-Tjeertes IF,et al.Developmental delay in moderately preterm-born children at school entry[J].The Journal of Pediatrics,2011,159(1):92-98.
[11] 殷张华,钱继红,王蓓,等.晚期早产儿近期并发症及智能发育前瞻性研究[J].中国新生儿科杂志,2015,30(2):112-116.
[12] Philippi H,Karch D,Kang KS,et al.Computer-based analysis of general movements reveals stereotypies predicting cerebral palsy[J].Developmental Medicine and Child Neurology,2014,56(10):960-967.
[13] Sustersic B,Sustar K,Paro-Panjan D.General movements of preterm infants in relation to their motor competence between 5 and 6 years[J].Eur J Paediatr Neurol, 2012,16(6):724-729.
[14] Mutlu A,Livanelioglu A,Korkmaz A.Assessment of "general movements" in high-risk infants by Prechtl analysis during early intervention period in the first year of life[J].The Turkish Journal of Pediatrics,2010,52(6):630-637.
[15] Romeo DM,Guzzetta A,Scoto M,et al.Early neurologic assessment in preterm- infants:integration of traditional neurologic examination and observation of general movements[J].Eur J Paediatr Neurol,2008,12(3):183-189.
[16] 鲍秀兰.新生儿行为能力和测查方法[J].实用诊断与治疗杂志,2003,17(6):441-443.
[17] 王艳娟,卢云,吴晓庆,等.新生儿神经行为测定在早产儿神经心理发育中的作用[J].中国妇幼保健,2013,28(1):71-73.
[18] 周洪涛,张惠佳,王跑球,等.Alberta婴儿运动量表与Peabody运动发育量表-2在脑损伤高危儿中的一致性研究[J].中国康复理论与实践,2013,19(6):556-558.
[19] Spittle AJ,Lee KJ,Spencer-Smith M,et al.Accuracy of two motor assessments during the first year of life in preterm infants for predicting motor outcome at preschool age[J].Plos One,2015,10(5):e0125854.
[20] de Albuquerque PL,Lemos A,Guerra MQD,et al.Accuracy of the Alberta Infant Motor Scale (AIMS) to detect developmental delay of gross motor skills in preterm infants:A systematic review[J].Developmental Neurorehabilitation,2015,18(1):15-21.
[21] Heidelise A,曹云.早产儿个体化神经发育支持医护模式[J].中国循证儿科杂志,2010,5(4):241-244.
[22] 周金君,李双双,顾瓅.新生儿个体化发育支持和评估项目在早期早产儿全身运动中的应用[J].中国儿童保健杂志,2015,23(1):109-110,112.
[23] Ohlsson A,Jacobs SE.NIDCAP:A systematic review and meta-analyses of randomized controlled trials[J].Pediatrics,2013,131(3):E881-E893.
[24] 陈光福,张蕴芳,陈美清,等.早产儿脑损伤早期干预模式与临床路径研究[J].中国当代儿科杂志,2014,16(1):35-39.

早产儿神经系统发育结局的研究进展

PDF

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

[1]	LI Xiaoqiang, GUO Zhirong, MA Zhengying, WANG Lixia, SHEN Wei. Feeding index and its influencing factors of preterm and low birth weight infants [J]. Chinese Journal of Child Health Care, 2024, 32(11): 1256-1260.
[2]	CUI Pengyuan, LI Guiping. Causal relationship between neonatalhy perbilirubinemia and tic disorder by Mendelian randomization [J]. Chinese Journal of Child Health Care, 2024, 32(10): 1116-1121.
[3]	. [J]. Chinese Journal of Child Health Care, 2024, 32(9): 929-933.
[4]	XIE Haixia, LUO Hongxia, LIU Haixia, SHAO Qinnan, FENG Guojun, WEN Yalan. Impact of histological chorioamnioitis on complications and neurodevelopment in premature infants at 1 year of age [J]. Chinese Journal of Child Health Care, 2024, 32(9): 947-952.
[5]	WEI Ping, WEI Jishan, HUANG Xuhua, ZHANG Yuxing, LIU Xianghong, HE Zhongbiao, MO Jingyuan, HUANG Zengshuai, YU Qun. Application of cardiac auscultation, pulse oximetry combine with oxygen inhalation in screening neonatal congenital heart disease in Guangxi Province [J]. Chinese Journal of Child Health Care, 2024, 32(9): 1034-1039.
[6]	WANG Xiuying, ZHENG Xiaoqin, ZOU Linli, DING Ling, FAN Ling, NIE Jing. Comparison of early catch-up growth among different types of small for gestational age infants and relevant influencing factors [J]. Chinese Journal of Child Health Care, 2024, 32(6): 613-618.
[7]	WANG Yinfei, YIN Qin, ZENG Sijie, SUN Lei, YAN Qinhui, SHENG Xiaojing. Differences in exosome miRNAs in human breast milk between preterm and full-term infants [J]. Chinese Journal of Child Health Care, 2024, 32(4): 377-383.
[8]	YU Hanshu, SUN Ruizhen, YANG Yanling, SU Yuehua, FU Zhongying. Effectiveness of extensively hydrolyzed formula in treating feeding intolerance in preterm infants [J]. Chinese Journal of Child Health Care, 2024, 32(4): 456-459.
[9]	HUANG Wanyi, ZHANG Youxiang, OU Qiaoqun, LIU Yuanchun, GUO Jiayu. Effects of gestational diabetes mellitus on brain development and miRNAs expression profile in neonatal mice [J]. Chinese Journal of Child Health Care, 2024, 32(2): 154-158.
[10]	LU Anfeng, HUANG Peilu, BI Lei, HUANG Guosheng, HUANG Haiyan. Physical and neuropsychological development of the offspring born to mother with gestational diabetes mellitus at 2 years old [J]. Chinese Journal of Child Health Care, 2024, 32(2): 208-211.
[11]	NING Yue, LUO Liyan, DUAN Jiang, XIE Yunbo, QI Zhiye, ZHANG Caiying, YANG Li, ZHONG Qinghua. Effects of different fortified feeding methods on the nutrient metabolism and growth rate of very low birth weight preterm infants [J]. Chinese Journal of Child Health Care, 2024, 32(1): 84-88.
[12]	CUI Hong. Premature infants need to be vigilant about spastic cerebral palsy [J]. Chinese Journal of Child Health Care, 2023, 31(11): 1165-1167.
[13]	WU Tong, JI Hong. Research advance in the relationship between hyperoxia and immature brain injury [J]. Chinese Journal of Child Health Care, 2023, 31(11): 1214-1218.
[14]	MA Hongfang, XUE Jiang, LIANG Shuang. Protective effect and mechanism of insulin-like growth factor 1 in preterm infants with white matter damage [J]. Chinese Journal of Child Health Care, 2023, 31(11): 1219-1224.
[15]	YOU Fang. Application of individualized vitamin D supplementation in very preterm infants [J]. Chinese Journal of Child Health Care, 2023, 31(10): 1127-1131.