Abstract

摘要： 注意力缺陷多动障碍(attention deficit hyperactivity disorder,ADHD)发病机制至今不明,其中讨论最热门的是多巴胺系统,其次是去甲肾上腺素系统。两者同属于单胺类神经递质,在生物合成、消除、酶降解及受体等方面有一定的相通性和特异性。本文综述了以上各个因素与ADHD发病及治疗的关系,多巴胺和去甲肾上腺素在ADHD发病及治疗方面具有双重作用,单独研究某个因素或某个系统具有一定的局限性。药物治疗研究过多侧重于单纯神经递质水平的变化,虽可以短期内明显改善ADHD核心症状,却忽视了对长期治疗效果的研究,尤其是ADHD共患病,从而也局限了ADHD的治疗。

关键词: ADHD, 多巴胺, 去甲肾上腺素

CLC Number:

R749.94

雷爽综述, 韩新民审校. 注意力缺陷多动障碍与多巴胺、去甲肾上腺素关系的研究进展[J]. 中国儿童保健杂志, 2013, 21(9): 953-955.

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注意力缺陷多动障碍与多巴胺、去甲肾上腺素关系的研究进展

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