Analysis of detective results on allergens in asthmatic children in Zhoushan islands
- XU Yu-lan
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Abstract
Objective To understand the allergy in asthmatic children of Zhoushan islands. Method A total of 246 children with asthma were tested for total IgE and 14 kinds of specific-IgE in serum by enzyme-linked immune assay(ELISA). Results Allergens were confirmed in 76.42%(188/246) of serum speciments,51.21%(126 /246)of them had at least 2 allergens,25.20%(62/246) had a single allergent.Among the children with inhaled allergens,most were caused by mite allergen,which was followed by house dust; seefood and beans were major sources for ingested allergens.Infants were more likely to be affected by ingested allergens while school-age children were majorly affected by inhaled allergens. Conclusion Allergens in the Zhoushan region mainly originate from mite,house dust and seefood.Most children with asthma are related to allergens,and allergens are related to age.
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References
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[4] Geldon JC,Milton DK,Ramsey CD,et al.Exposure to dust mite allergen and endotoxin in early life and asthma and atopy in childhood[J].J Allergy Clin Immunol,2007,120(1):144-149.
[5] Platts-Mills TA,Erwin EA,Heymann PW,et al.Pro:The evidence for a causal role of dust mies in asthma[J].Am J Respair Crit Care Med,2009,180(2):109-113.
[6] 董蔚,盛军,顾秀明,等.上海嘉定地区儿童过敏原调查及过敏原与支气管哮喘的相关性[J].中国当代儿科杂志,2011,14(7):521-523.
[7] 罗芳,邱晓梅,王玥,等.温州地区哮喘儿童过敏原检测的临床意义[J].浙江临床医学杂志,2008,10(3):366-367.
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