Meta-analysis on the efficacy of family interventions for children with cerebral palsy

doi:10.11852/zgetbjzz2024-1104

Abstract

Abstract: Objective To systematically evaluate the efficacy of home-based interventions in improving gross motor function and activities of daily living (ADL) in children with cerebral palsy (CP), so as to provide evidence for developing effective intervention strategies. Methods Literature on home-based interventions for children with CP were searched across databases including CNKI, VIP, Wanfang, CBM, PubMed, Embase, Web of Science, and Cochrane Library from inception to June 2024.Meta-analysis was performed using Review Manager 5.4 and Stata 17.0. Results A total of 28 studies were included.Meta-analysis revealed statistically significant differences between the home-based intervention group and conventional rehabilitation group in GMFM-88 scores (MD=10.87, 95% CI: 8.51 - 13.23), GMFM-88 E dimension scores (MD=4.71, 95% CI: 3.82 - 5.61), and ADLs scores (MD=7.63, 95% CI: 4.68 - 10.57) (P<0.001).However, no significant difference was observed in GMFM-66 scores (MD=4.43, 95% CI: －1.56 - 10.42, P=0.15)between the two groups. Conclusion Home-based interventions can effectively improve gross motor function and ADL performance in children with cerebral palsy.

Key words: cerebral palsy, family intervention, gross motor function, activities of daily living, Meta-analysis

摘要： 目的系统评价家庭干预对脑瘫儿童粗大运动功能及日常生活活动能力的疗效,为制定有效的干预策略提供依据。方法检索知网、维普、万方、CBM、PubMed、Embase、Web of Science、Cochrane Library中家庭干预治疗脑瘫儿童的研究文献,时限为建库至2024年6月。采用Review Manager 5.4和Stata17.0进行Meta分析。结果最终纳入28篇文献,Meta分析结果显示,家庭干预组与常规康复组GMFM-88评分(MD=10.87,95%CI:8.51~13.23)、GMFM-88 E区评分(MD=4.71,95%CI:3.82~5.61)、ADLs评分(MD=7.63,95%CI:4.68~10.57)差异有统计学意义(P<0.001),两组儿童GMFM-66评分差异无统计学意义(MD=4.43,95%CI:-1.56~10.42,P=0.15)。结论家庭干预能够有效改善脑瘫儿童粗大运动功能及日常生活活动能力。

关键词: 脑性瘫痪, 家庭干预, 粗大运动功能, 日常生活活动能力, Meta分析

CLC Number:

R179

FANG Enhui, GUAN Hui, TIAN Jinxin, ZHANG Hao, MA Lihong. Meta-analysis on the efficacy of family interventions for children with cerebral palsy[J]. Chinese Journal of Child Health Care, 2025, 33(12): 1358-1366.

房恩慧, 管惠, 田金鑫, 张浩, 马丽虹. 家庭干预治疗脑性瘫痪儿童疗效的Meta分析[J]. 中国儿童保健杂志, 2025, 33(12): 1358-1366.

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