Follow-up study on the effects of comprehensive intervention on children with autism spectrum disorder

ZHANG Ting; SHAO Zhi; YANG Guang; TAO Hongmei; PENG Shuai; ZHANG Yaru; WANG Yi; PENG Yuanqin

doi:10.11852/zgetbjzz2022-1400

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Chinese Journal of Child Health Care ›› 2023, Vol. 31 ›› Issue (9) : 969-974. DOI: 10.11852/zgetbjzz2022-1400

Original Articles

Follow-up study on the effects of comprehensive intervention on children with autism spectrum disorder

ZHANG Ting¹, SHAO Zhi^1,2, YANG Guang², TAO Hongmei^1,2, PENG Shuai¹, ZHANG Yaru^1,2, WANG Yi¹, PENG Yuanqin¹

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Abstract

Objective To analyze the changes in clinical symptoms, language ability, social adaptation, social communication, and Theory of Mind (ToM) skills of children with autism spectrum disorder (ASD) for 1 year after intervention cessation, who have already finished comprehensive intervention and had improved clinical symptoms and social adaptation. Methods Thirty-five children with ASD diagnosed in Chongqing Rehabilitation and Treatment Center for Children with ASD from 2015 to 2020 were selected in this study, and 35 typically developed children were enrolled. ASD children were 3 to 7 years old when receiving intervention, with an average age of (4.60±1.14) years old. ASD children were assessed at pre-intervention (T1), post-intervention (T2), and 1 year after the end of the intervention (T3) by the Childhood Autism Rating Scale (CARS), Psycho-Educational Profile, 3rd edition (PEP-3), Wechsler Preschool and Primary Scale of Intelligence, 4th edition (WPPSI-Ⅳ), Normal Development of Social Skills from Infant to Junior High School Children(S-M), Social Responsiveness Scale (SRS) and ToM task, while the typically developed children received assessment by WPPSI-Ⅳ, SRS and ToM task. Results Comprehensive intervention significantly improved clinical symptoms, social adaptation and language development of ASD children. There was no significant change in CARS scores between T2 and T3. Children with ASD showed significantly lower SRS score and ToM abilities compared to the typically developed children. CARS scores at T2 and T3, as well as WPPSI-Ⅳ intelligence quotient at T3 significantly predicted ToM ability of ASD children at T3. S-M score at T2 significantly predicted SRS score of ASD children at T3. Conclusions The improvements in clinical symptoms and social adaptation that ASD children gained with comprehensive interventions remain stable after the intervention is withdrawn. The development of ToM and social communication abilities in ASD children is influenced by different psychological abilities.

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autism spectrum disorder / comprehensive intervention / follow-up study

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ZHANG Ting, SHAO Zhi, YANG Guang, TAO Hongmei, PENG Shuai, ZHANG Yaru, WANG Yi, PENG Yuanqin. Follow-up study on the effects of comprehensive intervention on children with autism spectrum disorder[J]. Chinese Journal of Child Health Care. 2023, 31(9): 969-974 https://doi.org/10.11852/zgetbjzz2022-1400

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