Abstract: Objective To observe the influence of vitamin D supplementation on small fontanel pediatric growth of head circumference and Bayley intelligence test results. Methods 118 healthy infants aged 3months hospitalized in our Hospital from January 2010 to November 2011 were selected as the objects of the study.They were divided into two groups according to the fontanel inclined length.one was small fontanels group, the other was normal group.All infants were treated with vitamin D to prevent rickets.the head circumference of them were measured three points at 3 months, 12 months, 18 months and at 6 months, 18months the two points respectively Bayley intelligence test to evaluation analysis of their correlation. Results There were no statistically significant differences in the values of head circumference between the two groups at the age of 3 months, 12 months, 18 months and the values of head circumference between the two groups and the corresponding age of pediatric were not statistically significant different.Bayley intelligence test Results in two groups of the children at 6 months, 18 months were normal. Conclusions Vitamin D has no adverse effect on the skull growth of children with small anterior fontanel.It is necessary to take vitamin D for rickets prevention whatever the size of anterior fontanel.

Key words: vitamin D, small fontanel, growth of head circumference, Bayley intelligence test

摘要： 目的 探讨婴幼儿补充维生素D对小囟门儿童头围发育及Bayley智力测评结果的关系。方法 选择2010年1月-2011年11月在湖州市妇幼保健院体检的正常儿童118例作为观察对象, 分为小囟门组和正常对照组, 均给与维生素D, 分别在月龄3、12、18个月三个时间节点测量头围值, 同时在6、18个月两个时间节点做Bayley智力测试。结果 小囟门组与对照组儿童在3、12、18个月头围值差异均无统计学意义(P>0.05);两组与相应年龄小儿头围正常值比较差异无统计学意义(P>0.05);两组儿童6、18个月Bayley智力测试结果均为正常。结论 服用预防剂量的维生素D不会影响小囟门儿童头围的发育及智能发育, 无论前囟大小均应服用预防剂量的维生素D。

关键词: 维生素D, 小囟门, 头围发育, Bayley智力测评