Abstract: 【Objective】 To explore the screening of retinopathy of prematurity(ROP),and to understand the incidence and the related factors of ROP. 【Method】 On the May 10,2010 to March 31,2012 period in Qingyuan City Maternal and Child Heath Hospital outpatient department of ophthalmology for ROP screening of premature and low birth weight infants were retrospectively analyzed,statistics and analysis of screening. 【Results】 Screening a total of 239 cases of premature infants and low birth weight infants,ROP patients were found in 15 cases,the incidence rate of 6.28%.Statistical analysis showed that BW≤1 500 g,1 500 g<BW ≤2 000 g,BW>2 000 g ROP occurrence rate was respectively 20.59%,8.22%,1.52%.There were significant differences in the morbidity(χ²=17.47,P<0.005);GA≤31 weeks,31<GA≤34 weeks,GA>34 weeks the incidence of ROP were 29.17%,7.25%,2.06%.There also were significant differences in the morbidity(χ²= 25.96,P<0.005).The analysis also showed the occurrence of ROP and oxygen had a certain relationship. 【Conclusions】 Screening shows the incidence of ROP was 6.28%,standard oxygen,low birth weight and small for gestational age is the relevant factors of ROP.For low gestational age or low weight in high-risk preterm infants shound be regularly eyeground screening.

Key words: premature infant, retinopathy of prematurity, related factor

摘要： 【目的】 对早产儿视网膜病变(retinopathy of prematurity,ROP)进行筛查,了解ROP的发病情况及其相关影响因素。 【方法】 对眼科门诊进行ROP筛查的早产儿及低体重儿进行回顾性调查,统计筛查情况。 【结果】 共计筛查239例早产儿、低体重儿,发现ROP患儿15例,发生率为6.28%。BW≤1 500 g、1 500 g<BW≤2 000 g、BW>2 000 g的ROP的发生率分别为20.59%、8.22%、1.52%,组间ROP发生率差异有统计学意义(χ²=17.47,P<0.005);胎龄≤31周、31<胎龄≤34周、胎龄>34周的ROP的发生率分别为29.17%、7.25%、2.06%,组间ROP发生率差异也有统计学意义(χ²=25.96,P<0.005)。分析显示ROP的发生与吸氧有一定的关系。 【结论】 筛查显示ROP的发生率为6.28%,不规范吸氧、出生体重低及胎龄小是ROP形成的相关因素,对于低胎龄或低体重的高危早产儿应定期进行眼底筛查。

关键词: 早产儿, 视网膜病变, 相关因素