Abstract: 【Objective】 To increase the appreciation of manifestation through the analysis of clinical features in children with Asperger syndrome. 【Method】 Information on chief complaints, clinical manifestation, family backgrounds, gestational and perinatal factors, and the Wechsler intelligence quotient results of patients with Asperger syndrome from November 2006 to February 2011 were studied. 【Results】 1)19 cases were diagnosed with Asperger syndrome at the average age of (80.7±21.4) months and a male to female ratio of 18:1; 2) The most common manifestations were poor peer relationship (100%), attention deficit (94.7%), difficulty to comprehend semantics (89.5%), restricted interests (84.2%), clumsiness (78.9%), hyperactivity (78.9%), deficiency in nonverbal communication (73.7%), repetitive and stereotyped patterns of behaviors (73.7%);3) There were similar problems in several children's fathers, and most parents especially fathers had high degree;4) Verbal IQ was often higher than performance IQ in Wechsler intelligence. 【Conclusion】 Manifestations of Asperger syndrome are not only specific but also occult, the clinical recognition of these features is important for early identification and diagnosis.

Key words: Asperger syndrome, clinical features, Wechsler intelligence quotient

摘要： 【目的】 探讨阿斯伯格综合征的特点,提高对其认识和诊断水平。 【方法】 分析2006年11月-2011年2月期间在复旦大学附属儿科医院诊治的阿斯伯格综合征患儿的主诉、临床特点、家庭背景、妊娠期及围生期不良因素、韦氏智力结构特点。 【结果】 1)确诊的19名患儿,男女比例为18:1,被诊断的平均年龄为(80.7±21.4)个月;2)最常见的临床表现:伙伴关系不良(100%),注意力障碍(94.7%),语意理解困难(89.5%),局限兴趣(84.2%),动作笨拙(78.9%),多动(78.9%),非语言交流缺陷(73.7%),重复刻板行为(73.7%);3)患儿父亲中有类似问题的占到一定比例,且大多数父母特别是父亲的文化水平较高;4)韦氏智力测评显示大多数患儿言语IQ>操作IQ。 【结论】 阿斯伯格综合征的临床表现有其独特的特异性和隐匿性,熟悉和识别这些特征,有助于早期识别和诊断阿斯伯格综合征。

关键词: 阿斯伯格综合征, 临床特征, 韦氏智商