Study on the relationship between the blood lead level and behavior problems in the preschool children aged 3～7 years old in Shunyi district

Abstract

Abstract: 【Objective】 To observe blood lead level and distributed characteristics among children of 3～7 years old in Shunyi district in Beijing and to explore the effects of lead poisoning on preschool children behaviors. 【Methods】 1 307 children of 3～7 years old were investigated from April to June 2009. All subjects were selected from 5 kindergartens through a clustered-random sampling in Shunyi district.Blood lead level was measured and behavior problems were made by CBCL.All children were divided into 2 group(high blood lead group and low blood lead group)by blood lead beyond or below 100 μg/L .The behavior problems were identified while the total crude scores of CBCL beyond 42 in boys and 45 in girls. 【Results】 The geometric mean of blood lead was (3.328±2.765) with 1.22% of those ≥100 μg/L,and 0.15%≥200 μg/L.The median of CBCL total crude scores in high blood lead group was significantly higher than those of low blood lead group(P<0.001).The ratio of behavior problems in high blood lead group(76.47%) was significantly higher than that of low blood lead group(10.85%)(P<0.001).The ratios of behavior of attack, hyperactivity and disobey were significantly higher in high blood lead group than those of low blood lead group in boys(P<0.05). The ratio of behavior of disobey was significantly higher in high blood lead group than that of low blood lead group in girls(P<0.001). 【Conclusions】 Preschool children lead poisoning is associated with their behavior problems. Promoting healthy information can alleviate danger of high blood lead.

Key words: high blood lead, preschool children&apos, s health, behavior problems

摘要： 【目的】了解北京市顺义区3～7岁学龄前儿童血铅水平,分析其分布规律,初探铅暴露对3～7岁学龄前儿童行为问题产生的影响。【方法】采用整群随机抽样的方法于2009年4-6月对顺义区5所幼儿园1 307名3～7岁在园儿童采集手指末梢血测定血铅水平,同时采用Achenbach量表(Child Behavior Checklist, CBCL)进行行为问题评估。按照检测的血铅值将研究对象分为高血铅组(≥100 μg/L)和低血铅组(<100 μg/L)。男童CBCL总粗分≥42分,女童≥45分即判定为有行为问题。【结果】北京市顺义区3～7岁学龄前儿童血铅对数均值为3.328±2.765,血铅值≥100 μg/L占总测查人数的1.22%,血铅值≥200 μg/L占0.15%。高血铅组行为问题检出率为76.47%,低血铅组CBCL行为问题检出率为10.85%。高血铅组CBCL粗分及行为问题检出率均显著高于低血铅组,差异有高度统计学意义(P<0.001)。男童高血铅组在攻击因子、多动因子、违纪因子检出率显著高于低血铅组(P<0.05),女童高血铅组违纪因子检出率显著高于低血铅组(P<0.001)。【结论】高血铅的学龄前儿童行为问题较血铅值<100 μg/L儿童多,今后应加大宣传力度,降低铅中毒对学龄前儿童的危害。

关键词: 高血铅, 学龄前儿童健康, 行为问题

CLC Number:

R179
R749.94

LIU Ya-jing, JIA Mei-xiang, HE Ya-ping, WANG Xiu-yun, XIANG Zheng, CUI Wen-hong, LI Xue-ling, LIU Jian-hua, JI Wei-long. Study on the relationship between the blood lead level and behavior problems in the preschool children aged 3～7 years old in Shunyi district[J]. journal1, 2011, 19(8): 743-745.

刘雅静,贾美香,何亚萍,王秀云,项征,崔文红,李雪玲,刘建华,冀伟龙. 顺义区3～7岁学龄前儿童血铅水平与行为问题关系的研究[J]. 中国儿童保健杂志, 2011, 19(8): 743-745.

References

[1] Bernard SM. Should the center for disease contorl and prevention's childhood lead poisoning intervention level be lowered?[J]. Am J Public Health,2003,93(8):1253-1260.
[2] Zhang SM, Dai YH, Xie XH, et al. Surveillance of childhood blood lead levels in 14 cities of China in 2004-2006[J]. Biomed Environ Sci,2009,22(4):288-296.
[3] CDC. Laboratory standardization: lead. Atlanta, GA: centers for disease control and prevention[R/OL]. 2006,http:∥www.cdc.gov/nceh/dls/lead.html.
[4] Binns HJ, Campbell C, Brown MJ. Interpreting and managing blood lead levels of less than 10 μg/dL in children and reducing childhood exposure to lead: recommendations of the Centers for Disease Control and Prevention Advisory Committee on childhood lead poisoning prevention[J]. Pediatrics,2007,120(5):e1285-e1298.
[5] Brown MJ. Interpreting and managing blood lead levels <10 μg/dL in children and reducing childhood exposures to lead: recommendations of CDC's Advisory Committee on Childhood Lead Poisoning Prevention [J]. MMWR Recomm Rep,2007,56(RR-8):1-16.
[6] 梁晓红,朱兰芳,刘秋华,等.4～5岁学龄前儿童血铅与行为问题关系的研究[J].中国妇幼保健,2006,21(21):2955-2957.
[7] Bellinger DC. Very low lead exposures and children's neurodevelopment[J].Curr Opin Pediatr,2008,20(2):172-177.
[8] Lanphear BP, Hornung R, Khoury J, et al. Low-level environmental lead exposure and children's intellectual function: an international pooled analysis[J]. Environ Health Perspect,2005,113(7):894-899.
[9] Brubaker CJ, Schmithorst VJ, Haynes EN, et al. Altered myelination and axonal integrity in adults with childhood lead exposure: a diffusion tensor imaging study[J]. Neurotoxicology,2009,30(6):867-875.
[10] 余高妍,颜崇淮,余晓刚,等.慢性中度铅中毒对幼兔海马组织的影响[J].中华预防医学杂志,2008,42(3):160-164.

[1]	JIN Chunyan, ZHU Zhu. Relationship between lifestyle and mental health in preschool children [J]. Chinese Journal of Child Health Care, 2024, 32(3): 255-260.
[2]	CHENG Fengjie, LI Jing. Dyadic parent-child interaction coding system and its application [J]. Chinese Journal of Child Health Care, 2024, 32(2): 159-163.
[3]	GAO Liru, QIN Yiming, QU Zhiyong. Randomized controlled trial of the evidence-based therapy based on behavioral parent training group in alleviating Chinese children with symptoms of externalized behavior problems [J]. Chinese Journal of Child Health Care, 2023, 31(9): 957-962.
[4]	WANG An-yun, LIU Zhi-chen, FAN Jing-yi. Emotional and behavior problems and dietary behavior problems in preschool children with autism spectrum disorder [J]. Chinese Journal of Child Health Care, 2022, 30(9): 1019-1023.
[5]	YUAN Ling-hao, WEI Bing, YUE Xiao-zhe, QI Shuang-hui, WANG Huan, JIA Jing-jing, LIAO Shi-e. Behavioral problems and its influencing factors of 4- to 6-year-old children in Shenyang [J]. Chinese Journal of Child Health Care, 2022, 30(4): 436-440.
[6]	HE Hong-ling, LIU Yu-chen, ZHANG Da-wei, LI Na, MA Ming-fang, LIU Hui, YANG Lu, GAO Cheng-ge, HUANG Yan-ping. Study on changes for behavior problems of 4- to 6-year-old children in Xi'an in 2007 and 2018 [J]. journal1, 2021, 29(1): 79-83.
[7]	YANG Jing,WANG Dan,WU Ping-ping,XIAN Ya-jing,LIN Su-lan. Study on the correlation between family nurture environment and eating behavior problems of children aged 3-6 years in Urumqi [J]. journal1, 2019, 27(3): 251-254.
[8]	ZHANG Peng-fei, LUO Yan. Review of methods for assessing mealtime behaviors in children with autism spectrum disorder [J]. journal1, 2019, 27(12): 1327-1330.
[9]	ZOU Qiu-yan, JIANG Yan-rui, MA Xi-rui, ZHANG Yi-wen. Study on behavior problems in children with abnormal language development [J]. journal1, 2018, 26(4): 368-371.
[10]	MU Li-juan, LV Ying, ZHAO Jing, LI He-li, LI Rong-ping, ZHANG Ya-ya. Study on correlation between family rearing environment and behavior development of 3~6 years old children [J]. journal1, 2018, 26(1): 63-66.
[11]	DING Jun-li, YUE Rui-zhi, HAO Ai-zhen, WANG Yu-ting, CHEN Zhi-guo. Study on the influence of family environment on behavior problems of children aged 3~6 [J]. journal1, 2018, 26(1): 88-90.
[12]	YANG Geng-lin, Gulibakeranmu·abudula, Weina·aishanbai, Mailikaimu·abudukelimu. A relationship study of the temperament and the behavior problems in 8~12 ages Kazakand children [J]. journal1, 2017, 25(5): 505-507.
[13]	YANG Geng-lin,Wena·aishanbai,Mailikaimu·abudukelimu,DING Ling,WANG Ling-li,Ainiwa·xiaokelati. Comparative study of the temperament,the behavior problems and parental rearing patterns in 8～12 years old children among Uyghur ethnicity,Kazakand ethnicity and Han ethnicity [J]. journal1, 2017, 25(3): 309-311.
[14]	TIAN Tian, SONG Jia, QIN Yue-yi, ZHANG Dan, LI Jing, HU You-fang. Study on the relationship between home nurture environment and behavior problems of preschool children in Jiangsu province [J]. journal1, 2017, 25(12): 1215-1217.
[15]	FANG Hong-ying,TANG Yin-xia.. Analysis of emotional and behavioral problems and its influencing factors of preschool children in Tongling city. [J]. journal1, 2016, 24(6): 632-634.