Relationship between breast development age of idiopathic central precocious puberty girl and maternal age at menarche and maternal height
- FENG Bing1, LI Gui-mei2, QU Jing-shi1, MA Li-xia1
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Abstract
【Objective】 To study the association between breast development age of idiopathic central precocious puberty(ICPP) girl and maternal age at menarche and maternal Height. 【Methods】 1) ICPP group included 43 cases and SPT group included 41 cases and 30 cases as control group. 2)Compared the maternal age at menarche and height among ICPP,SPT and control groups. 3)Linear correlation analysis was made between the age of breast development and maternal age at menarche and height in ICPP girls. 【Results】 1)Maternal age at menarche in ICPP group were significantly lower than SPT group[(11.66±1.35)ears vs (12.93±1.66)ears, P<0.01] and than control group[( 11.66±1.35)ears vs (14.03±0.58)ears,P<0.01).There was no significantly difference of them between SPT and control group(P>0.05). 2)The maternal height in ICPP group was significantly lower than both SPT and control group[(154.13±3.61)cm vs (159.80±4.71)cm, (154.13±3.61)cm vs (159.5±2.33)cm P<0.01 respectively]. 3)There were significanly linear correlation between the age at breast development and maternal age at menarche and height in ICPP(P<0.01, respectively). 【Conclusions】 1)Breast development age of idiopathic central precocious puberty(ICPP) girl has a large correlation with maternal age at menarche and maternal height. 2)Short stature of ICCP girl and mother may have correlation with their early puberty or ICPP.
Key words
idiopathic central precocious puberty / simple premature thelarche / short stature / the age of breast development / maternal age at menarche
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References
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[4] Bar-El DS, Reifen R. Soy as an endocrine disruptor: cause for caution? [J]. J Pediatr Endocrinol Metab,2010,23(9):855-861.
[5] 中华医学会儿科学分会内分泌遗传代谢学组.中枢性(真性)性早熟诊治指南[J].中华儿科杂志,2007,45(6):426-427.
[6] Su PH, Wang SL, Chen JY, et al. A study of anthropomorphic and biochemical characteristics in girls with central precocious puberty and thelarche variant[J]. J Pediatr Endocrinol Metab,2008,21(3):213-220.
[7] 李成娟,季成叶.遗传与环境因素对女性青春期性征发育影响[J].中国学校卫生,2006,27(10):834-835.
[8] 张璇.上海市儿童少年性发育的现况调查[S].2002年.中国学位论文全文数据库.





