【Objective】 To explore the influence of birth weight on infant's early physical, intellectual and motor development, and provide scientific evidences for early health education of macrosomia. 【Methods】 The physical and motor development characteristics of the two groups in different periods were selected by regular tracing the macrosomia and term infants appropriate for gestational age who were born in obstetric department of the maternal and child health hospital of Shenzhen. And intellectual and motors development of two infant groups were evaluated when they were one year old by using Bayley Scales of Infant Development. 【Results】 The weight, height and head circumference developmental status of Macrosomia were significantly better than those of term infants appropriate for gestational age (P＜0.05).There was no significant difference between the two groups of children within one year of age in developmental milestones (P＞0.05). The moter development index of macrosomia was significantly higher than that of term infants appropriate for gestational age (P＜0.05). 【Conclusions】 The physical developmental status of normal macrosomia are significantly better than those of term infants appropriate for gestational age. Heavier weight has no significant effects on developmental milestones and the intellectual and motor development of children.