【Objective】 To study the differences between autism spectrum disorders(ASD) and developmental language disorders(DLD) in pathogenesis related factors(risk factors and clinical manifestations). 【Methods】 This retrospective study compared risk factors and clinical manifestations of 39 toddlers(aged 2-5y) with ASD and 46 toddlers with DLD using detailed questionnaires containing 16 items, then analysed data by t test, chi-square test, rank test . 【Results】 Children with ASD had prominent impairments in socialization language, especially, in the age calling mother(or other caregivers) consciously(P<0.05). While there were no differences in other factors(including: premature birth, birthrank, birth mode, asphyxia, birth weight, birth injury, head injury, convulsion, major illnesses, caregivers,parents reproductive age, family history)(P>0.05). Children with ASD were often observed and sent to doctors because of language delay(78.28%), social problems(78.28%), behavioral problems(36.57%) . And the mean age of first diagnosis was 39 months. 【Conclusions】 Children with ASD have prominent impairments in socialization language, more sever than children with DLD. The language delay and social problems are more likely to be observed by caregivers of children with ASD. The first diagnosis of children with ASD is often delayed .
Key words
autistic spectrum disorders /
developmental language disorder /
risk factors /
retrospective study
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References
[1] Buschmann A, Jooss B, Rupp A, et al. Children with developmental language delay at 24 months of age: Results of a diagnostic work-up[J]. Dev Med Child Neurol,2008,50(3):223-229. [2] 金星明.儿童孤独症临床进展[J].中国儿童保健杂志,2007,15(5):451-452.
[3] 金志娟,金星明.学龄前儿童普通话平均句子长度的多因素研究[J].中国儿童保健杂志,2009,17(1):524-525.
[4] 金星明.儿童发育性语言延迟的干预[J].实用儿科临床杂志,2006,21(23):1605-1607.
[5] 章依文,金星明,沈晓明,等.2～3岁儿童语言发育迟缓筛查标准的建立[J].中国儿童保健杂志,2003,11(5):308-310.
[6] Dover CJ, Le Couteur A. How to diagnose autism[J]. Arch Dis Child,2007,92:540-545.
[7] Pamela V, Jamie, Juhi, et al. Differ-entiating between autism spectrum disorders and other developmental disabilities in children who failed a screening instrument for ASD[J]. J Autism Dev Disord,2007,(37):425-436.
[8] 赵夏薇,毛萌.孤独症临床危险因素相关研究与进展[J].中国儿童保健杂志,2008,16(1):67-69.
[9] 艾戎,王宁,童雪涛.儿童孤独症的早期临床表现[J].实用儿科临床志,2010,25(12):913-915.
[10] Barbaro J, D issanayake C. Autism spectrum disorder in infancy and toddlerhood: A review of the evidence on early signs, early diagnosis[J]. J Dev Behav Pediatr,2009,30(5):447-459.
[11] Michael LRJ. Progress in understanding autism: 2007~2010[J]. Autism Dev Disord,2011,41:395-404.
[12] Pancsofar N, Vernon FL. Mother and father language input to young children: Contributions to later language development[J]. J App l Dev Psycho,2006,27(6):571-587.
[13] Grether JK, Anderson MC, Croen LA, et al. Risk of autism and increasing maternal and paternal age in a large north American population[J]. Am J Epidemiol,2009,170(9):1118-1126.
[14] Chuang YC. Hsu CY. Chiu NC, et al. Other impairment associated with developmental language delay in preschool-aged children[J]. Journal of Child Neurology,2011,26(6):714-717.
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