Abstract: Objective To investigate the nutritional status of children aged 1 - 5 years with cerebral palsy in Shenzhen, and to determine its influencing factors, in order to provide evidence for clinical nutritional intervention. Methods This multicenter study was performed in ten maternal and child healthcare hospitals from October 2020 to August 2022. A total of 1 094 1- to 5-year-old children with cerebral palsy were involved in the survey. General data of the children were collected, meanwhile body weight, height/body length were measured. Nutritional status was evaluated according to the child growth and development standards issued by WHO. Multivariate Logistic regression analysis was performed to test factors that may affect nutritional status. Results The prevalence of malnutrition among children with cerebral palsy aged 1 - 5 years was 17.91%. GMFCS level, feeding difficulty and parental knowledge level of nutrition were the factors significantly influencing the nutritional status of children with cerebral palsy (P<0.05). Higher GMFCS score and feeding difficulty were the risk factors for malnutrition with cerebral palsy, while parental knowledge level of nutrition was a protective factor. There was no significant difference in the prevalence of malnutrition among children with different clinical classification, constipation or not, same educational background of parents (P >0.05). Conclusions The malnutrition prevalence rate in children with cerebral palsy aged 1 - 5 years appears to be low in Shenzhen, China. GMFCS levels, the severity of feeding difficulties, and parental knowledge level of nutrition are factors that affect the nutrition status of this population.

Key words: cerebral palsy, malnutrition, Gross Motor Function Classfication System, multicenter study

摘要： 目的 调查深圳市1~5岁脑性瘫痪儿童营养现状以及影响因素分析,为营养干预提供依据。方法 由深圳市儿童医院康复医学科组织深圳市妇幼保健院等10家妇幼保健院康复医学科参与协作的多中心研究,选择2020年10月—2022年8月各中心诊断脑性瘫痪1~5岁儿童共1 094名,搜集一般资料,同时进行身长/身高、体重测量以及问卷调查。参照WHO发布的儿童生长发育标准评价儿童营养状况,并对可能影响营养状况的因素进行多因素Logistic回归分析。结果 1 094名脑瘫儿童营养不良患病率为17.91%。 GMFCS等级、喂养困难程度、父母营养知识掌握水平是影响脑瘫儿童营养状况的因素,差异有统计学意义(P＜0.05),其中GMFCS增加、喂养困难程度加重是脑瘫儿童营养不良的危险因素,父母营养知识掌握程度好是其保护性因素。临床分型、便秘与否、父母亲学历与营养不良患病率无显著相关性(P＞0.05)。结论 深圳市1~5岁脑瘫儿童营养不良发病率较低,GMFCS等级、进食困难程度、父母营养知识掌握程度均是影响脑瘫营养的因素,日后营养干预重点应从上述因素着手。

关键词: 脑性瘫痪, 营养不良, 粗大运动功能分级系统, 多中心研究