Abstract: Objective To investigate nutrition status of low birth weight infants (LBWI) with different gestational ages,and to provide theoretical evidence for rational nutrition intervention. Methods LBWI with different gestational ages who were treated in Fujian Provincial Hospital were selected as research participants.After nutrition intervention,their blood biochemical indexes were observed and the time of enteral nutrition reaching DRIs was recorded. Results According to different gestational ages,participants were divided into 3 groups,group Ⅰ (gestational age 28~31 weeks),group Ⅱ(gestational age 32~36 weeks),group Ⅲ(gestational age 37~42 weeks).Compared with group Ⅰ,the time for enteral nutrition reaching DRIs were significantly shortened in group Ⅱ and group Ⅲ (P<0.05).The differences of the time for enteral nutrition reaching DRIs in group Ⅱ and group Ⅲ were not statistically significant (P>0.05).In terms of 1 d biochemical index,ALB in group Ⅱ and group Ⅲ significantly increased than group Ⅰ (P<0.05);Compared with group Ⅲ,TC in group Ⅰ and group Ⅱ obviously decreased,and HDL-C,LDL-C and ApoB in group Ⅰ and group Ⅱ all obviously increased with significant differences (P<0.05).In terms of the 1 d biochemical index after enteral nutrition reaching DRIs,GLu in group Ⅱ and group Ⅲ significantly increased than that in group Ⅰ (P<0.05);Compared with group Ⅱ,ALB,TC,TG in group Ⅰ and group Ⅲ all obviously decreased,HDL-C,LDL-C and ApoA all obviously increased,and the difference was statistically significant (P<0.05). Conclusion Blood lipid level detection should be conducted in low birth weight infants with different gestational ages,and reasonable nutritional intervention is suggested to adopt according to early evaluation Results .

Key words: ow birth weight, premature infants, nutritional status, dietary reference intakes, evaluation

摘要： 目的 调查分析不同胎龄低出生体重新生儿营养状况,为合理的营养干预提供理论依据。方法 选择2016年福建省立医院重症医学五科收治的不同胎龄低出生体重新生儿,予以营养干预后,对其血生化指标进行观测,并记录肠内营养达到DRIs的时间。结果 根据不同胎龄分为三组,其中Ⅰ组(胎龄28~31周),Ⅱ组(胎龄32~36周),Ⅲ组(胎龄37~42周),与Ⅰ组比较,Ⅱ、Ⅲ组肠内营养达到DRIs的时间明显缩短,差异具有统计学意义(P<0.05),Ⅱ、Ⅲ组间比较,肠内营养达到DRIs的时间差异无统计学意义(P>0.05)。出生第1 d生化指标而言,与Ⅰ组比较,Ⅱ、Ⅲ组的ALB升高明显,差异具有统计学意义(P<0.05),与Ⅲ组比较,Ⅰ、Ⅱ组的TC降低明显,HDL-C、LDL-C以及ApoB均升高明显,差异具有统计学意义(P<0.05)。肠内营养达到DRIs后的第1 d生化指标而言,与Ⅰ组比较,Ⅱ、Ⅲ组的GLu升高明显,差异具有统计学意义(P<0.05),与Ⅱ组比较,Ⅰ、Ⅲ组的ALB、TC、TG降低明显,HDL-C、LDL-C以及ApoA均升高明显,差异具有统计学意义(P<0.05)。结论 对于不同胎龄的低出生体重儿应对其进行血脂水平检测,根据早期评估结果予以合理的营养干预。

关键词: 低出生体重, 早产儿, 营养状况, 膳食营养素参考摄入量, 评估