Objective To investigate and assess the growth and development,rate of caries,hepatitis B surface antigen positive and anemia of preschool children in Nanning city for the purpose of further improvement of children's nutritional status and physical fitness. Methods A toatl of 761 preschool children aged 2 to 7 years old were extracted from six kindergartens in Nanning city.The data of weight,height,dental caries,anti-HBS and hemoglobin were collected,analyzed and compared to evaluate the growth and development and health situation of preschool children in Nanning. Results Children's height and weight in this study were lower than those of the national standards,and upper- middle and lower-middle levers of the ratio of height and weight were majority.Caries rate was 31.93%,dental caries number was 4.71 per capita.Caries rate in boys was higher than that in girls.Caries rate increased gradually with age and reached a peak in 5~6 years age group (50.62%).Total anti-HBS positive rate was 68.78%,65.65% in <3 age group,69.9% in 3~4 age group,68.26% in 4~5 age group,72.7% in 5~6 age group,58.06% in 6~7 age group.Total anemic rate was 6.22%,5.88 % in <3 age group,9.41% in 3~4 age group,4.13% in 4~5 age group,6.71% in 5~6 age group,3.17% in 6~7 age group. Conclusions The overall level of preschool children's nutrition in Nanning city is low,and the health awareness need to be improved.Health education for preschool children on balance diet caries prevention and vaccination should be strengthened.