Abstract: Objective To determine the bone mineral density of tibia in healthy children aged 3~6 years old in Zibo area and set up normal reference value of speed of sound(SOS) for preschool children. Methods 7 920 children aged 3~6 years old,who hand body examination in kindergarten were selected and according to the age divided into 12 groups ( every 3 months apart as a group).Their tibias SOS were assayed by adopting quantitative ultrasound system.Height and weight of subjects were measured, and body mass indexes were calculated.The data were analyzed by using SPSS 20.0 software. Results With the age increasing,the values of tibias SOS increased in general more over,SOS was closely related positively to age(r=0.209,P＜0.01).There were significant differences of SOS between boys and girls aged 3~6 years old within the same age group (P＜0.05).There were significant differences of SOS between healthy children and obese children aged 3~6 years old within the same age group (P＜0.05). Conclusions SOS of tibias are related to age.SOS of tibias are different between male and female in preschool children,and SOS of tibias of obese children are lower than the other children.The reference value of SOS should be set up according to the age and sex.

Key words: tibias, bone mineral density, quantitative ultrasound, preschool child

摘要： 目的 检测淄博市城区3～6岁儿童胫骨骨强度水平,建立本地区学龄前儿童超声骨强度声速值(speed of sound,SOS)正常参考值。方法 选择淄博市城区幼儿园参加体格检查的3～6岁儿童,根据月龄将7 920名儿童分为12组。采用定量超声仪测定儿童左侧胫骨中段SOS值,同时测量受检者身高、体重,应用SPSS 20.0软件进行统计学分析。结果 随着年龄增长,SOS在总体上呈增加趋势,且与年龄呈正相关(r=0.209,P＜0.01),各年龄组男女童之间、各年龄组肥胖儿童与非肥胖儿童之间SOS值比较差异均有统计学意义(P值均＜0.05)。结论 SOS值与年龄相关,且具有性别差异,肥胖儿童SOS值较低,应根据不同年龄、性别建立儿童SOS参考值。

关键词: 胫骨, 骨强度, 定量超声, 学龄前儿童