斜视性弱视与屈光参差性弱视多焦视觉诱发电位的对比研究

中国儿童保健杂志 ›› 2012, Vol. 20 ›› Issue (2): 171-174.

斜视性弱视与屈光参差性弱视多焦视觉诱发电位的对比研究

刘晖¹,陈霞²

1 天津市妇女儿童保健中心,天津 300074;
2 天津医科大学眼科临床学院,天津 300020

收稿日期:2011-11-08 发布日期:2012-02-06 出版日期:2012-02-06
通讯作者: 陈霞,E-mail:chenxia9453@yahoo.com.cn
作者简介:刘晖(1977-),女,主治医师,硕士研究生,研究方向为斜视弱视与小儿眼科

Investigation of multifocal visual evoked potential in strabismic and anisometropic amblyopes.

LIU Hui¹,CHEN Xia²

1 Tianjin Women's and Children's Health Center,Tianjin 300074,China;
2 Tianjin Eye Hospital,Tianjin 300020,China

Received:2011-11-08 Online:2012-02-06 Published:2012-02-06

摘要/Abstract

摘要： 【目的】研究斜视性弱视与屈光参差性弱视患者弱视眼与对侧眼的多焦视觉诱发电位(multifocal visual evoked potential,mVEP)的特征性变化,探讨两种不同类型弱视的发病机理。【方法】采用美国EDI公司生产的VERIS ScienceTM4.2多焦电生理系统对31例屈光参差性弱视患者、30例斜视性(内斜)弱视患者及30例正常人双眼分别进行图形mVEP检测,以潜伏期与振幅为分析指标,进行了屈光参差性弱视眼、对侧眼和正常对照三组mVEP的对比研究。【结果】六个离心度上弱视眼反应振幅密度较其对侧眼和正常眼均显著降低,潜伏期延长(P＜0.01)。正常对照组及屈光参差性弱视组中鼻侧网膜与颞侧网膜反应振幅密度差异均无统计学意义,而斜视性(内斜)弱视组中,鼻侧网膜反应振幅密度均小于颞侧网膜。【结论】不同类型弱视可能具有不同的神经机制,mVEP检查可为弱视的诊断、治疗和预后判断提供客观依据。

关键词: 斜视, 屈光参差, 弱视, 多焦视觉诱发电位

Abstract: 【Objective】 To study the characteristic changes of multifocal VEP in strabismic and anisometropic amblyopes,and evaluate the mechanism of amblyopia. 【Methods】 The multifocal pattern VEP of both eyes of 30 strabismic amblyopes,31 anisometropic amblyopes and 30 normal subjects were recorded by VERIS ScienceTM4.2 multifocal visual evoked response imaging system made of America EDI company.The latencies and amplitudes of P waves were analysed.Changes were investigated by comparing the amblyopic eyes,the fellow eyes of the patients and the normal eyes. 【Results】 At six eccentricities the amplitudes of P waves of the amblyopic eyes were reduced and the latencies of P waves were markedly prolonged compared with the fellow eyes and the normal eyes.The mean amplitude of mVEP in the nasal retinal hemifields was smaller than in the temporal retinal hemifields in strabismic amblyopes. 【Conclusion】 Different types of amblyopia may have different neural mechanisms,the results suggest that multifocal VEP could be used in instructing the diagnosis and treatment of amblyopia.

Key words: strabismus, anisometropia, amblyopia, multifocal VEP

中图分类号:

R779.7

刘晖,陈霞. 斜视性弱视与屈光参差性弱视多焦视觉诱发电位的对比研究[J]. 中国儿童保健杂志, 2012, 20(2): 171-174.

LIU Hui,CHEN Xia. Investigation of multifocal visual evoked potential in strabismic and anisometropic amblyopes.[J]. journal1, 2012, 20(2): 171-174.

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