可穿戴设备评估儿童神经发育障碍的研究进展

doi:10.11852/zgetbjzz2024-0926

摘要/Abstract

摘要： 神经发育障碍(NDDs)是一组常见的疾病,表现为儿童时期开始的神经系统发育和功能障碍。神经发育障碍研究迫切需要实用的方法进行早期诊断与防治。本文介绍了应用可穿戴设备评估儿童神经发育障碍疾病的现状和展望。

Abstract: Neurodevelopmental disorders (NDDs) are a group of common conditions characterized by developmental and functional impairments of the nervous system beginning in childhood.There is an urgent need for practical methods for the early diagnosis and prevention of NDDs.This review discusses the current situation and prospects of wearable electronic devices in assessing neurodevelopmental disorders in children.

Key words: wearable electronic devices, neurodevelopmental disorders, human activity recognition, children

中图分类号:

R179

潘彦铮, 付竹梅, 计岳龙. 可穿戴设备评估儿童神经发育障碍的研究进展[J]. 中国儿童保健杂志, 2025, 33(6): 633-637.

PAN Yanzheng, FU Zhumei, JI Yuelong. Advances in wearable devices for assessing childhood neurodevelopmental disorders[J]. Chinese Journal of Child Health Care, 2025, 33(6): 633-637.

参考文献

[1] Thapar A, Cooper M, Rutter M.Neurodevelopmental disorders[J].Lancet Psychiat, 2017, 4(4): 339-346.
[2] Solmi M, Radua J, Olivola M, et al.Age at onset of mental disorders worldwide: Large-scale Meta-analysis of 192 epidemiological studies[J].Mol Psychiatry, 2022(27): 281-295.
[3] Pierrat V, Marchand L, Marret S, et al.Neurodevelopmental outcomes at age 5 among children born preterm: EPIPAGE-2 cohort study[J].BMJ, 2021(373): n741.
[4] Jeste SS.Neurodevelopmental behavioral and cognitive disorders[J].Continuum, 2015, 21(3): 690-714.
[5] Deloitte Australia.The social and economic costs of ADHD in Australia[EB/OL].[2024-08-01].https://www.deloitte.com/au/en/services/economics/perspectives/social-economic-costs-adhd-Australia.html.
[6] Kularatna S, Jadambaa A, Senanayake S, et al.The cost of neurodevelopmental disability: Scoping review of economic evaluation methods[J].ClinicoEconomics Outcomes Res, 2022(14): 665-682.
[7] Licari MK, Alvares GA, Varcin K, et al.Prevalence of motor difficulties in autism spectrum disorder: Analysis of a population-based cohort[J].Autism Res, 2020, 13(2): 298-306.
[8] Miller HL, Sherrod GM, Mauk JE, et al.Shared features or co-occurrence? Evaluating symptoms of developmental coordination disorder in children and adolescents with autism spectrum disorder[J].J Autism Dev Disord, 2021, 51(10): 3443-3455.
[9] Miller HL, Licari MK, Bhat A, et al.Motor problems in autism: Co-occurrence or feature?[J].Dev Med Child Neurol, 2024, 66(1): 16-22.
[10] 国家卫生健康委.国家卫生健康委关于印发贯彻2021-2030年中国妇女儿童发展纲要实施方案的通知[EB/OL].(2022-04-09)[2024-07-22].http://www.nhc.gov.cn/fys/s7900/202204/acaaffebf2e44964a9b14fdddd173cfa.shtml.
[11] 邹红, 朱健芳, 罗佳怡, 等.孤独症谱系障碍的干预方法及发展趋势[J].中国儿童保健杂志, 2024, 32(3): 317-321.
Zou H, Zhu FJ, Luo JY, et al.Intervention methods and development trends of autism spectrum disorder[J].Chin J Child Health Care, 2024, 32(3): 317-321.(in Chinese)
[12] Cainelli E, Bisiacchi P.Neurodevelopmental disorders: Past, present, and future[J].Children, 2022, 10(1): 31.
[13] Marschik PB, Pokorny FB, Peharz R, et al.A novel way to measure and predict development: A heuristic approach to facilitate the early detection of neurodevelopmental disorders[J].Curr Neurol Neurosci Rep, 2017, 17(5): 43.
[14] 赵晓茹, 李钦, 赵广平, 等.神经发育障碍的早期自动化筛查技术[J].教育生物学杂志, 2023, 11(3): 225-230.
Zhao XR, Li Q, Zhao GP, et al.Early automated screening technology for neurodevelopmental disorders[J].J Biol Educ, 2023, 11(3): 225-230.(in Chinese)
[15] 朱红敏, 袁纯辉, 刘智胜.儿童神经发育障碍疾病研究进展[J].中国当代儿科杂志, 2023, 25(1): 91-97.
Zhu HM, Yuan CH, Liu ZS.Research progress on neurodevelopmental disorders in children[J].Chin J Contemp Pediatr, 2023, 25(1): 91-97.(in Chinese)
[16] 彭仲康, 崔兴然, 张政波, 等.可穿戴设备:评估与监测人体生理状态的展望[J].生物医学工程学杂志, 2023, 40(6): 1045-1052.
Peng ZK, Cui XR, Zhang ZB, et al.Wearable electronic devices: A prospect for assessing and monitoring the physiological state of the human body[J].J Biol Eng, 2023, 40(6): 1045-1052.(in Chinese)
[17] 中华医学会儿科学分会发育行为学组, 中国医师协会儿科分会儿童保健专业委员会, 儿童孤独症诊断与防治技术和标准研究项目专家组.孤独症谱系障碍儿童早期识别筛查和早期干预专家共识[J].中华儿科杂志, 2017, 55(12): 890-897.
Developmental Behavior Group of the Pediatric Branch of the Chinese Medical Association, Child Health Care Professional Committee of the Pediatric Branch of the Chinese Medical Doctor Association, Expert Group of the Diagnosis and Prevention of Autism in Children and Standards Research Project.Expert consensus on early identification, screening and early intervention in children with autism spectrum disorder[J].Chin J Appl Clin Pediatr,2017, 55(12): 890-897.(in Chinese)
[18] 中华医学会儿科学分会神经学组, 中国医师协会神经内科分会儿童神经疾病专业委员会.儿童智力障碍或全面发育迟缓病因诊断策略专家共识[J].中华儿科杂志, 2018, 56(11): 806-810.
Neurology Group, Pediatric Branch, Chinese Medical Association, Pediatric Neurological Disease Professional Committee, Neurology Branch, Chinese Medical Doctor Association.Expert consensus on diagnostic strategies for the etiology of intellectual disability or global developmental delay in children[J].Chin J Appl Clin Pediatr,2018, 56(11): 806-810.(in Chinese)
[19] 中华医学会儿科学分会发育行为学组.注意缺陷多动障碍早期识别、规范诊断和治疗的儿科专家共识[J].中华儿科杂志, 2020, 58(3): 188-193.
Developmental Behavior Group Pediatric Branch Chinese Medical Association.Pediatric expert consensus on early identification, standardized diagnosis and treatment of attention deficit hyperactivity disorder[J].Chin J Appl Clin Pediatr, 2020, 58(3): 188-193.(in Chinese)
[20] Zwaigenbaum L, Bauman ML, Stone WL, et al.Early identification of autism spectrum disorder: Recommendations for practice and research[J].Pediatrics, 2015, 136(Suppl):10-40.
[21] Han YL, Sulaiman WSW, Badayai ARA, et al.Systematic review of translation and cultural adaptations of autism spectrum disorder′s screening tool: The Modified Checklist for Autism in Toddlers, Revised (M-CHAT-R)[J].F1000Research, 2023(12):471.
[22] Li C, Zhu G, Feng J, et al.Improving the early screening procedure for autism spectrum disorder in young children: Experience from a community-based model in Shanghai[J].Autism Res, 2018, 11(9): 1206-1217.
[23] Siu AL, US Preventive Services Task Force (USPSTF), Bibbins-Domingo K, et al.Screening for autism spectrum disorder in young children: US preventive services task force recommendation statement[J].JAMA, 2016, 315(7): 691-696.
[24] Pierce K, Gazestani VH, Bacon E, et al.Evaluation of the diagnostic stability of the early autism spectrum disorder phenotype in the general population starting at 12 months[J].JAMA Pediatr, 2019, 173(6): 578-587.
[25] Allison C, Williams J, Scott F, et al.The Childhood Asperger Syndrome Test (CAST): Test-retest reliability in a high scoring sample[J].Autism, 2007, 11(2): 173-185.
[26] Zheng Y, Du Y, Su LY, et al.Reliability and validity of the Chinese version of Questionnaire - Children with Difficulties for Chinese children or adolescents with attention-deficit/hyperactivity disorder: A cross-sectional survey[J].Neuropsychiatr Dis Treat, 2018(14): 2181-2190.
[27] 黄环环, 何凡.儿童注意缺陷多动障碍常见精神科共患病及治疗[J].中国实用儿科杂志, 2023, 38(8): 588-592.
Huang HH, He F.Common psychiatric comorbidities and treatment of attention deficit hyperactivity disorder in children[J].Chin J Prac Pediatr, 2023, 38(8): 588-592.(in Chinese)
[28] 江英婵, 张勇勤, 张琦, 等.数字健康技术在缓解围生期女性负性情绪中应用的研究进展[J].护理研究, 2024, 38(17): 3087-3093.
Jiang YC, Zhang YQ, Zhang Q, et al.Research progress on the application of digital health technology in alleviating negative emotions in perinatal women[J].Nurs Res, 2024, 38(17): 3087-3093.(in Chinese)
[29] Straczkiewicz M, James P, Onnela JP.A systematic review of smartphone-based human activity recognition methods for health research[J].NPJ Digit, 2021, 4(1):1-15.
[30] Franchak JM, Scott V, Luo C.A contactless method for measuring full-day, naturalistic motor behavior using wearable inertial sensors[J].Front Psychol, 2021(12): 701343.
[31] 王瑞, 吕蓉, 梁涛.可穿戴设备在疾病管理中的应用进展[J].中华护理杂志, 2018, 53(1): 114-116.
Wang R, Lv R, Liang T.Advances in the application of wearable devices in disease management[J].Chin J Nurs, 2018, 53(1): 114-116.(in Chinese)
[32] Ciarmoli D, Stasolla F.New technologies to support people with neurodevelopmental disorders: A selective review[J].OBM Neurobiol, 2023, 7(1): 1-32.
[33] Novak I, Morgan C, Adde L, et al.Early, accurate diagnosis and early intervention in cerebral palsy: Advances in diagnosis and treatment[J].JAMA Pediatr, 2017, 171(9): 897-907.
[34] Rihar A, Mihelj M, PašičJ, et al.Infant posture and movement analysis using a sensor-supported gym with toys[J].Med Biol Eng Comput, 2019, 57(2): 427-439.
[35] Wedyan M, Al-Jumaily A.Upper limb motor coordination based early diagnosis in high risk subjects for autism[C]//2016 IEEE Symposium Series on Computational Intecligence.doi: 10.1109/SSCI.2016.7849893.
[36] Braito I, Maselli M, Sgandurra G, et al.Assessment of upper limb use in children with typical development and neurodevelopmental disorders by inertial sensors: A systematic review[J].J NeuroEng Rehabil, 2018, 15(1): 94.
[37] Airaksinen M, Räsänen O, Ilén E, et al.Automatic posture and movement tracking of infants with wearable movement sensors[J].Sci Rep, 2020(10): 169.
[38] Airaksinen M, Gallen A, Kivi A, et al.Intelligent wearable allows out-of-the-lab tracking of developing motor abilities in infants[J].Commun Med, 2022, 2(1): 1-14.
[39] Airaksinen M, Taylor E, Gallen A, et al.Charting infants′ motor development at home using a wearable system: Validation and comparison to physical growth charts[J].E Bio Medicine, 2023(92): 104591.
[40] Wilson RB, Vangala S, Elashoff D, et al.Using wearable sensor technology to measure motion complexity in infants at high familial risk for autism spectrum disorder[J].Sensors, 2021, 21(2):616.
[41] Siddiqui U, Ullah F, Iqbal A, et al.Wearable-sensors-based platform for gesture recognition of autism spectrum disorder children using machine learning algorithms[J].Sensors, 2021(21): 3319.
[42] Deng W, Nishiyori R, Vanderbilt DL, et al.How many days are necessary to represent typical daily leg movement behavior for infants at risk of developmental disabilities?[J].Sensors, 2020, 20(18):5344.
[43] Wilson RB, Vangala S, Reetzke R, et al.Objective measurement of movement variability using wearable sensors predicts ASD outcomes in infants at high likelihood for ASD and ADHD[J].Autism Res,2024, 17(6):1094-1105.
[44] Fioriello F, Maugeri A, D′Alvia L, et al.A wearable heart rate measurement device for children with autism spectrum disorder[J].Sci Rep, 2020,10(1):18659.
[45] Pittella E, Piuzzi E, Rizzuto E, et al.Wearable heart rate monitoring as stress response indicator in children with neurodevelopmental disorder[J].IEEE MeMeA,2018. doi:10.1109/MeMeA.2018.8438805.
[46] Imbiriba T, Demirkaya A, Singh A, et al.Wearable biosensing to predict imminent aggressive behavior in psychiatric inpatient youths with autism[J].JAMA Netw Open, 2023, 6(12): e2348898.
[47] Faedda GL, Ohashi K, Hernandez M, et al.Actigraph measures discriminate pediatric bipolar disorder from attention-deficit/hyperactivity disorder and typically developing controls[J].JCPP, 2016, 57(6): 706-716.
[48] Airaksinen M, Vanhatalo S, Räsänen O.Comparison of end-to-end neural network architectures and data augmentation methods for automatic infant motility assessment using wearable sensors[J].Sensors, 2023, 23(7): 3773.
[49] Welch V, Wy TJ, Ligezka A, et al.Use of mobile and wearable artificial intelligence in child and adolescent psychiatry: Scoping review[J].J Med Int Res, 2022, 24(3): e33560.
[50] Chen X, Kim DH, Lu N.Introduction: Wearable devices[J].Chem Rev, 2024, 124(10): 6145-6147.
[51] Marzena SM, Micai M, Caruso A, et al.Technologies to support the diagnosis and/or treatment of neurodevelopmental disorders: A systematic review[J].Neurosci Biobehav Rev,2023(145):105021.
[52] Lobo MA, Hall ML, Greenspan B, et al.Wearables for pediatric rehabilitation: How to optimally design and use products to meet the needs of users[J].Phys Ther, 2019, 99(6): 647-657.