关键词: 先天性, 消化道畸形, 影响因素

Abstract: 【Objective】 Through researching the characteristics and prognostic influential factors of the hospitalized infants with congenital digestive tract malformation aged 0~3 months, the present study aims at providing a scientific guideline for the establishment of an effective emergency rescue system for it. 【Methods】 Subjects were 466 hospitalized infants with congenital digestive tract malformation in the Neonatal Surgery Department of Hunan Children's Hospital within one year. Their basic features and influential factors on the outcome of these infants were analyzed by the approaches of single factor logistic regression analysis and multiple factor logistic regression analysis. 【Results】 The number of infants with congenital digestive tract malformation was 466, with 332 boys (71.24%) and 134 girls (28.76%), and with 367 rural patients (78.76%) and 99 urban patients (21.24%). The rural patients were much easier to suffer from such complications than urban patients as fluid and electrolyte imbalance, pneumonia, peritonitis, digestive tract perforation, malnutrition and so on. 385 cases of the patients were cured, accounting for 82.62%; 13 cases (2.79%) got better; 32 cases (6.87%) gave up and 36 cases (7.73%) died. And among the dead cases, there were 32 rural patients and 4 urban patients. The fatality rate of infants in rural areas was higher than that in urban areas. Through the application of single factor logistic regression analysis, the influential factors on the outcome of hospitalized infants with congenital digestive tract malformation were infectious shock, respiratory failure, septicemia, DIC, scleredema etc. Through the application of the multiple factor logistic regression analysis, the influential factors were respiratory failure, digestive tract perforation, septicemia and onset of disease. 【Conclusions】 The prognosis of congenital digestive tract malformation is closely related to such factors as infectious shock, respiratory failure, digestive tract perforation, septicemia, DIC, scleredema and so on. Countryside is the emphasis of prevention and treatment of congenital digestive tract malformation. In order to elevate the recovery rate, we should carry out prenatal diagnosis and early diagnose, popularize the knowledge of diagnose digestive tract malformation in countryside, give early operations and raise the level of treatment of the hospital.

Key words: congenital, digestive tract malformation, influential factors