关键词: 全身运动评估, 脑电图, 高危新生儿, 运动发育结局, 脑性瘫痪

Abstract: Objective To analyze prechtl's qualitative general movements assessment(GMs) and electroencephalogram(EEG) of children with different motor development outcomes retrospectively and investigate the GMs value in predicting of cerebral palsy. Methods The GMs and EEG reports of children more than one-year-old who had been hospitalized in neonatal intensive care unit were collected.The diagnosis of cerebral palsy was made according to the international cerebral palsy diagnostic definition published in 2006.Stata 11.0 was used to analyze GMs positive predictive values,negative predictive values,specificity and sensitivity among different groups and the difference of EEG. Results A total of sixty-two children were enrolled,28 of them were diagnosed as cerebral palsy,11 were motor retardation and 23 were normal.The predictive validity of GMs was as following:sensitivity 96.4%,specificity 73.9%,positive predictive value 81.8% and negative predictive value 94.4%.The rate of abnormal GMs in children of cerebral palsy was significantly higher than that in motor retardation and normal children.The rate of abnormal EEG in children of cerebral palsy and motor retardation were 78.6% and 81.8% respectively,higher than that in normal children(53.3%).The abnormalities of EEG mainly were sharp wave,sharp slow wave,high voltage and slow basic activities. Conclusions GMs assessment could be used in high risk infants within 4 to 5 months to give a reliable and valid prediction for later motor development outcome,especially for cerebral palsy.Application of GMs and EEG would help comprehensive assessment of patients' function status.

Key words: prechtl's qualitative general movements assessment, electroencephalogram, high risk infant, motor development outcome, cerebral palsy