关键词: 低出生体重, 视觉诱发电位, 纵向随访, 早产儿

Abstract: Objective To explore the evolution of flash visual evoked potentials (FVEP) in preterm infants from 1 to 36 months,and compare to the full-term. Method Using the Viking-Ⅳ visual electrophysiological testing device,the latency and amplitude values of the P2 main wave on FVEPs were recorded in infants longitudinally at 1,3,6,9,12,18,24 and 36 months. Results The trends of FVEPs were similar in the three groups of children,the latency of the P2 showed a significant decrease along with the age,but the amplitude had no difference.The latency of the P2 was more significantly delayed in VLBW group than in full-term group from 1 to 24 months,but there was no significant difference at 36 months; the LBW group showed the latency of the P2 wave was significantly delayed compared with the full-term group,only in 1~6 months. Conclusions Premature and LBW have the negative influence on the development of children's visual system,especially for VLBW.The follow-up evaluation of visual function state of this preterm group should be strengthened in school-age period.

Key words: low birth weight, flash visual evoked potentials, longitudinal study, preterm infants