中国儿童保健杂志 ›› 2024, Vol. 32 ›› Issue (11): 1261-1265.DOI: 10.11852/zgetbjzz2024-0187

• 临床研究 • 上一篇    下一篇

儿童发育性髋关节发育不良发生危险因素及预测模型构建

马晓鹏1, 李兴珍1, 谢坤霞1, 刘甜1, 郝婷婷2   

  1. 1.延安大学附属医院儿科,陕西 延安 716000;
    2.延安大学附属医院消化内科
  • 收稿日期:2024-02-26 修回日期:2024-06-05 发布日期:2024-11-04 出版日期:2024-11-10
  • 通讯作者: 郝婷婷,E-mail:ht-1951@sohu.com
  • 作者简介:马晓鹏(1981-),男,本科学历,副主任医师,主要研究方向为儿童保健、生长发育、儿童康复。

Development risk factors and prediction model construction of children with developmental hip dysplasia

MA Xiaopeng1, LI Xingzhen1, XIE Kunxia1, LIU Tian1, HAO Tingting2   

  1. 1. Department of Pediatrics, Affiliated Hospital of Yan'an University, Yan'an, Shaanxi 716000, China;
    2. Department of Gastroenterology,Affiliated Hospital of Yan'an University
  • Received:2024-02-26 Revised:2024-06-05 Online:2024-11-10 Published:2024-11-04
  • Contact: HAO Tingting, E-mail: ht-1951@sohu.com

摘要: 目的 探讨儿童发育性髋关节发育不良(DDH)发生危险因素并构建相关预测模型,旨在为临床筛查防治工作提供更多信息。方法 回顾性纳入2018年1月—2023年12月于延安大学附属医院诊治DDH患儿62例,并以1∶1匹配纳入同期体检健康儿童62例作为对照;对儿童DDH发生情况及其危险因素进行分析。结果 纳入的62例DDH患儿中右侧30例,左侧32例;Graf分型Ⅱa(+)型、Ⅱa(-)型、Ⅱb型、Ⅱc型、D型、Ⅲ型及Ⅳ型分别为15例、22例、7例、6例、5例、6例、1例。单因素分析结果显示,性别、分娩胎位、是否早产儿、有无包被绑腿习惯及家族遗传史均可能与儿童DDH发生有关(P<0.05)。Logistic多因素分析结果证实,女性、臀位分娩、非早产儿、有包被绑腿习惯及家族遗传史均是儿童DDH发生的独立危险因素(P<0.05)。利用回归模型的独立影响因素以及P值预测概率对儿童DDH发生风险进行预测,约登指数分别为37.50%、14.83%、81.42%、25.00%、8.69%、82.42%。结论 女性、臀位分娩、非早产儿、存在包被绑腿习惯及家族遗传史的儿童更易出现DDH;利用以上5个因素构建的数据模型对于患者的死亡预测显示出良好的效能,值得在工作中深入分析。

关键词: 发育性髋关节发育不良, 预测模型, 儿童

Abstract: Objective To explore the risk factors for developmental dysplasia of the hip (DDH) in children and construct a relevant prediction model, in order to provide more information for clinical screening, prevention, and treatment of DDH. Methods A retrospective study was conducted involving 62 children with DDH diagnosed and treated at the Affiliated Hospital of Yan'an University from January 2018 to December 2023. Additionally, 62 healthy children undergoing physical examinations during the same period were matched at a 1∶1 ratio as the control group. The occurrence of DDH in children was analyzed, and the risk factors were explored. Results Among the 62 children with DDH included in this study, 30 had the affected hip on the right side, and 32 on the left side. According to the Graf classification, there were 15 cases of type Ⅱa(+), 22 cases of type Ⅱa(-), 7 cases of type Ⅱb, 6 cases of type Ⅱc, 5 cases of type D, 6 cases of type Ⅲ, and 1 case of type Ⅳ. Univariate analysis revealed that gender, fetal position during delivery, prematurity status, leg wrapping and leggings habits, and family history of DDH may be associated with the occurrence of DDH in children (P<0.05). Logistic multivariate analysis confirmed that female, breech delivery, non-prematurity, leg wrapping and leggings habits, and family history of DDH were independent risk factors for DDH in children (P<0.05). Using the independent influencing factors and P-value prediction probabilities from the regression model to predict the risk of DDH in children, the Youden indices were 37.50%, 14.83%, 81.42%, 25.00%, 8.69%, and 82.42%, respectively. Conclusions Children who are female, delivered in the breech position, non-premature, having leg wrapping and leggings habits and family history of DDH are more prone to developing DDH. The data model constructed using these five factors demonstrates good performance in predicting the occurrence of DDH in patients and is worthy of further analysis in clinical practice.

Key words: developmental dysplasia of the hip, prediction model, children

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