关键词: 婴儿, 极低出生体重, 早期营养, 体格发育, 智能发育

Abstract: Objective To explore the relationship of early nutrition and weight,height,head circumference growth and long-term neurological motor development,for the future clinical work in the very low birth weight infants (VLBWI). Methods A total of 86 VLBWI were selected in Nantong Maternal and Child Health Care Hospital NICU.According to the weight of hospital discharge,the cases were divided into extrauterine growth restriction (EUGR) and non-EUGR group,and followed up regularly at high risk infants follow-up clinic.Measurement of weight,length,head circumference,GMs quality assessment,head MRI examination,developmental quotient (DQ) assessment were operated regularly.Weight,length,head circumference growth and movement,neural development were observed in different groups. Results In EUGR group,when they were corrected for gestational age 6 months and 12 months,their length,head circumference were significantly lower than those in non EUGR group,the differences were statistically significant (P<0.05).The weight of EUGR group was lower than that of non EUGR group at corrected for gestational age 6 months,and the difference was statistically significant (P<0.05).The weight of EUGR group was not different from that of the non EUGR group at corrected for gestational age 12 months (P>0.05).The positive rates of GMs,head MRI in EUGR group were significantly higher than those in non-EUGR group (P<0.05).Developmental quotient <85 patients in the EUGR group had no difference than that in the non-EUGR group (P>0.05).But the average developmental quotient of EUGR group was significantly lower than that of non-EUGR group (P<0.05).The physical and intelligence development of the EUGR group of very low birth weight infants was significantly lower than that of the non EUGR group. Conclusion Much attention should be paid to their nutrition management to reduce the incidence of EUGR in very low birth weight infants.At the same time we need to pay attention to the management of the very low birth weight infants after discharge,to strengthen nutrition guidance of EUGR,and to make obvious catch-up growth trend.

Key words: infant,very low birth weight, early nutrition, physical development, intellectual development