Abstract: Objective To examine the seasonality of congenital hypothyroidism (CH) incidence and it's correlation with ambient temperature in Anhui province. Method Retrospective study of CH disease in 2001~2012 to analyzed the correlation with temperature by using Spearman's correlation analysis. Results In the 690 cases of CH,it had 34.78% distribution in the warm season and the rest of 65.22% distribution in the cold season,CH incidence in cold season was higher than that in warm season.Consequently,the difference was statistically significant (P<0.05).There was a certain correlation between the monthly incidence rate and environmental temperature.In the meantime,correlation between male group were significantly higher than that of female patients. Conclusion The CH incidence has certain characteristics,which has relevant to the change of the temperature and the season.

Key words: congenital hypothyroidism, seasonality, temperature, incidence

摘要： 目的 了解安徽省先天性甲状腺功能减低症(congenital hypothyroidism,CH)发病率与季节、温度之间的关系,为降低CH发病率提供科学依据。方法 通过对2001-2012年CH发病情况回顾性研究,采用Spearman相关分析来探讨发病率与环境温度之间的关系。结果 在690例CH中,有34.78%分布在暖季,65.22%分布在冷季,冷季发病率高于暖季,差异有统计学意义(P＜0.05)。月发病率与环境温度之间有一定相关性,男性患儿的相关性高于女性患儿。结论 安徽省CH发病率存在与季节及温度相关性特征。

关键词: 先天性甲状腺功能减低症, 季节性, 温度, 发病率