Abstract: 【Objective】 To observe the effect of Simo decoction,the condition of intolerant infants under Clostridium butyricum powder in treatment of neonatal asphyxia during perinatal period after feeding. 【Methods】 68 infants selected as cases and were randomly divided into the control group (n=36) and treatment group (n=32) cases with amniotic fluid meconium pollution in two groups were treated with gastric lavage,after gastric lavage they could not open the milk until fasting for 6 hours.The control group received the treatment of Combined Bacillus Subtilis and Enterococcus Faecium Granules with Multivitamines,Live,and the treatment group was treated with the Simo decoction,Clostridium butyricum powder treatment,daily record of vomiting,amount of milk,stool frequency,abdominal distention disappeared days of age,the days of birth weight,such as age of recovery. 【Results】 The experimental group reduced frequency of vomiting ,and vomiting,abdominal distension disappeared ahead of time,up to 50 kCal/(kg·d) days in advance,to restore the birth weight of the days in advance,with statistically significant (P<0.05). 【Conclusion】 The Simo decoction,Clostridium butyricum powder in treatment of neonatal asphyxia during perinatal period after feeding intolerance,can promote gastrointestinal functional maturation,improve feeding tolerance,and it's safe to human beings.

Key words: asphyxia during perinatal period, feeding intolerance, Simo decoction, Clostridium butyricum powder, neonatal

摘要： 【目的】 观察四磨汤、酪酸梭菌活菌散治疗新生儿围生期窒息后喂养不耐受的情况。 【方法】 选择本院有围生期窒息后喂养不耐受的新生儿68例为实验对象,并随机分为对照组(n=36)和治疗组(n=32),羊水有胎粪污染者,两组均予洗胃,洗胃后禁食6 h才开奶,对照组予枯草杆菌二联活菌颗粒治疗,治疗组予四磨汤、酪酸梭菌活菌散治疗。每天记录呕吐的次数、呕吐量、进食的奶量、大便次数、腹胀消失的日龄、恢复出生体重的日龄等。 【结果】 实验组呕吐次数减少、呕吐及腹胀消失时间提前、达50 kCal/(kg·d)日龄,恢复出生体重的日龄均提前,差异有统计学意义(P<0.05)。 【结论】 四磨汤、酪酸梭菌活菌散治疗新生儿围生期窒息后喂养不耐受,能促进胃肠功能成熟,提高喂养的耐受性,而且安全。

关键词: 围生期窒息后, 喂养不耐受, 四磨汤, 酪酸梭菌活菌散, 新生儿