Abstract: Objective To investigate the measures and clinical effect of early intervention on high risk infants. Methods A total of 253 high risk infants,who were treated in Maternity and Children Health Care Hospital between December 2008 and June 2010,were divided into invention group (125) and non-intervention group (128).Meanwhile,another (105) healthy children form a control group.The invention group of high risk infants was given regular medical examination and intelligence test as early intervention. Results The intelligence and motor development in intervention group of high-risk infants were significantly higher than those in non-intervention group,and the sequela incidence in intervention group was significantly lower than that in non-intervention group.These differences had statistical significances (P<0.05).The differences between intervention group and normal one in intelligence development,motor development and the sequela incidence had no statistical significances (P>0.05). Conclusions Early intervention in risky children helps their intelligence development,reducing the sequela incidence of nervous system and improving the patient's life quality.Early intervention pattern is family-centered,simply operated and acceptable.

Key words: high-risk infants, early intervention, clinical effect

摘要： 目的 探讨高危儿早期干预措施及其临床疗效。 方法 将2008年12月-2010年06月就诊的253例高危儿随机分为干预组(125例)和未干预组(128例),并设立正常儿对照组( 105例);对干预组高危儿实施早期干预,定期进行体格检查及智能发育测试。 结果 干预组高危儿的智能发育及运动发育均明显高于未干预组,后遗症的发生率明显低于未干预组,差异均有统计学意义(P<0.05) 。干预组高危儿的智力发育及运动发育、后遗症的发生率与正常儿对照组比较差异均无统计学意义(P>0.05)。 结论 早期干预对高危儿的智能发育有明显的促进作用,并可减少神经系统后遗症的发生率,提高患儿的生活质量。早期干预模式以家庭为中心,方法简单、易行,易于接受。

关键词: 高危儿, 早期干预, 临床效果