Abstract: 【Objective】 To observe the clinical characters and treatments of cow's milk protein allergy(CMPA)infants. 【Method】 23 cases were diagnosed as cow's milk protein allergy by CMP elimination in 2009, the clinical data were analyzed retrospectively. 【Results】 The patients consisted of 14 males and 9 females,whose course of disease ranged from 2 weeks to 3 months. The main clinical manifestation were chronic diarrhoea, bloody stool, vomiting or gastroesophageal reflux disease, constipation, food refusal and atopic eczema; Extensively hydrolyzed formula and probiotics improved the symptoms in all 23 cases. 【Conclusions】 The gastrointestinal symptoms caused by cow's milk protein allergy is nonspecific and diagnosis is difficult. Extensively hydrolyzed formula and probiotics can be used to confirm the diagnosis and improve the prognosis.

Key words: cow&apos, s milk protein allergy, gastrointestinal symptoms, extensively hydrolyzed formula, probiotics, infants

摘要： 【目的】 探讨小婴儿牛奶过敏的临床特点, 以提高临床诊治水平。 【方法】 回顾性总结2009年3月-2010年4月在本院采用饮食回避诊断治疗的牛奶过敏婴儿的临床资料。 【结果】 病程2周至2月不等,临床表现为慢性腹泻伴/不伴便血,呕吐,喂养困难或拒食,哭闹,便秘等,部分伴有湿疹;23例给予深度水解蛋白奶粉替代牛奶蛋白并辅以益生菌治疗后临床症状缓解。 【结论】 小婴儿牛奶过敏可以仅表现为胃肠症状,易误诊,深度水解蛋白奶粉和益生菌有利于确立诊断及缓解症状。

关键词: 牛奶过敏, 胃肠道症状, 深度水解蛋白奶粉, 益生菌, 婴儿