Objective To investigate the extremely low birth weight infant's (ELBWI) quality of life and related intervention measures through review of ELBWI's living condition from a single centre NICU in recently years. Method It was retrospectively analyzed about the clinical data of 32 patients of ELBWI from February 2000 to January 2012. Results The ELBWI suvival rate,mortality rate,abandon rate were 34.4%,25.0%,and 40.6%respectively.The Assisted Reproductive Technologies (ART) ELBWI suvival rate was 75.0%.Female suvival rate(72.7%) was higer than male's in all suvival patients.The common direct causes of death were pulmonary haemorrhage(62.5%),hyaline membrane disease (12.5%),intracranial haemorrhage(12.5%) and gastrointestinal bleeding(12.5%).The data were divided into two stages(February 2000~January 2006 vs February 2006~January 2012).Compared with the former group,the abandon rate of the later was obviously lower(28.0% vs 85.7%) and suvival rate was significantly higher (44% vs 0%).There was significant diffrence of ART between survival group and mortality/abandon group(P<0.05) with single factor analysis and logistic regression analysis. 【Conclutions】 Positive treatment and timely processing of complications can improve ELBWI survival rate and reduce mortality.The treatment of survival limits ELBWI should weigh up pros and cons,and should elevated the living quality of ELBWI.