Objective To investigate the incidence rate and high-risk factors of intrauterine growth restriction (IUGR) and its influence on fetal-neonatal healty. Methods 1)The incidence and high-risk factors of IUGR:From Jan.1,2011 to Dec.31,2011,the clinic data of maternal and newborn infants from six hospitals in China were retrospectively analysed.2)The influence of IUGR on fetal-neonatal health:the data from the NICU of Bayi Children's Hospital were analysed. Results 1) The incidence rate of IUGR was 8.77%.The IUGR incidence in females was 9.80% and it was 7.84% in males(P＜0.05),and the incidence of IUGR in preterm infants (16.43%) was higher than that of term infants (7.87%)(P＜0.01).2)Logistic analysis showed that hypertensive,abnormal amniotic fluid,and abnormality of umbilical cord were independent factors of IUGR.3)There were significantly higher incidence of complications in IUGR infants including hypoglycemia,asphyxia,hypoxic ischemic encephalopathy,gastrointestinal bleeding,congenital malformation,polycythemia,pneumorrhagia,apnea,congenital heart disease,and disseminated intravascular coagulation.Besides,IUGR prolonged their duration of hospital stayed and increased their hospitalization expenses markedly (P<0.05). Conclusion The overall incidence of IUGR is as high as 8.77% in China.IUGR has significantly adverse influence on fetal-neonatal health.These data provide some reference for maternal and perinatal health care.
Key words
intrauterine growth restriction /
incidence /
high-risk factors /
fetal-neonatal health
{{custom_sec.title}}
{{custom_sec.title}}
{{custom_sec.content}}
References
[1] Stefania L,Lina B,Lidia D,et al.Short-term and long-term sequelae in intrauterine growth retardation[J].J Matern Fetal Neonatal Med,2013,26(3):222-225.
[2] Kliegman RM.Intrauterine growth restriction[M].//Martin RJ,Fanroff AA,Walsh MC.Fanaroff and Martin's Neonatal Perinatal Medicine.9th edition,Elsever Mosby,Louis,USA,2011:245-275.
[3] Eleftheraddes M,Creatsas G,Nicolaides K.Fetal growth restriction and postnatal development[J].Ann NY Acad Sci,2006,1092:319-330.
[4] Leitner Y,Fattal-Valevski A,Geva R,et al.Neurodevelopmental outcome of children with intrauterine growth retardation:a longitudinal,10-year prospective study[J].J Child Neurol,2007,22(5):580-587.
[5] Rueda-Clausen CF,Morton JS,Davidge ST.Effects of hypoxia-induced intrauterine growth restriction on cardiopulmonary structure and function during adulthood[J].Cardiovasc Res,2009,81(4):713-722.
[6] Pylipow M,Spector LG,Puumala SE,et al.Early postnatal weight gain,intellectual performance,and body mass index at 7 years of age in term infants with intrauterine growth restriction[J].J Pediatr,2009,154(2):201-206.
[7] Fitzgerald K,Cai J,Hoff G,et al.Clinical manifestation of small-for-gestational- age risk pregnancy from smoking is gestational age dependent[J].Am J Perinatol,2007,24(9):519-524.
[8] Graner S,Klingberg-Allvin M,Phuc HD,et al.Adverse perinatal and neonatal outcomes and their determinants in rural Vietnam 1999-2005[J].Paediatr Perinat Epidemiol,2010,24(6):535-542.
[9] 王庆红,杨于嘉,魏克伦,等.我国小于胎龄儿现状分析[J].中国实用儿科杂志,2009,24(3):177-180.
[10] Jancevska A,Tasic V,Damcevski N,et al.Children born small for gestational age[J].Prilozi,2012,33(2):47-58.
[11] Jacobsson B,Ahlin K,Francis A,et al.Cerebral palsy and restricted growth status at birth:population-based case-control study[J].BJOG,2008,115:1250-1255.
PDF(566 KB)
